Mayo Clinic is designated by the National Cancer Institute as a comprehensive cancer center, with three locations: Rochester, Minnesota; Scottsdale/Phoenix, Arizona; and Jacksonville, Florida. And Mayo Clinic breast cancer scientists have research affiliations with national cancer research groups, such as:

Areas of research include:

  • Drugs to reduce cancer risk (chemoprevention) for postmenopausal women at high risk of developing breast cancer
  • The role of hormones in breast cancer prevention
  • Molecular breast imaging for evaluating breast symptoms and conditions
  • Biological markers that influence breast density on mammograms
  • Fluid retention and tissue swelling (lymphedema) in the breast after surgery
  • Infection prevention after breast and underarm (axillary) surgery
  • Low-dose vaginal estrogens for treating the thinning and inflammation of the vaginal wall (atrophic vaginitis)

Women's Cancer Program

Mayo Clinic doctors in the Women's Cancer Program conduct research in many areas to improve treatment for women who have breast and gynecological cancers. Some studies may help determine which women with noncancerous (benign) breast disease are at risk of developing breast cancer.

As part of the Mayo Clinic Cancer Center, the Women's Cancer Program provides psychological and social support classes, a resource center and educational programs for patients and their families.

Familial Cancer Program

Mayo Clinic's campus in Florida offers the Familial Cancer Program, a special research program for people at high risk of developing breast cancer based on family history.

Clinical trials

Mayo Clinic researchers are involved in studies to evaluate potential treatments (clinical trials) for many conditions and treatments, including breast cancer, chemotherapy, hormonal treatments, targeted biological therapies, radiation therapy, prevention of breast cancer, management of hot flashes, and treatment-related fatigue, nausea and cognitive dysfunction.

You may have the opportunity to participate in clinical trials, whether you are a newly diagnosed with breast cancer or are living with recurrent or advanced breast cancer. Ask your doctor about clinical trials that might be right for you.

Mayo's clinical trials include experimental treatments, often unavailable elsewhere, which frequently lead to improved patient care for people worldwide. Learn more about clinical trials at Mayo Clinic.


See a list of publications about breast topics by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

April 23, 2021
  1. National Accreditation Program for Breast Centers. American College of Surgeons. Accessed Feb. 7, 2019.
  2. Breast SPOREs. National Cancer Institute. Accessed Feb. 7, 2019.
  3. Find an NCI-designated cancer center. National Cancer Institute. Accessed Feb. 7, 2019.