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Below are current clinical trials.
Filter this list of studies by location, status and more.
Rochester, Minn.
This study is designed to determine if point-of-care washing of allogeneic Leukocyte-Reduced Red Blood Cells reduces pulmonary complications when compared to standard-of-care Leukocyte-Reduced Red Blood Cells in a cardiac surgical population.
The goal of this study is to better understand why anesthesia providers utilize albumin within the operative setting, to the area of clinical specialty, years of service, and position within the anesthesia department. With the knowledge obtained, department wide education will be developed and offered to all anesthesia providers imparting appropriate uses of albumin, based on the current research.
We will determine if a) glycyrrhetic acid (GA, a key component of TJ-68) evokes vasodilation, and b) if glycyrrhetic acid alters the TRP mediated sensory response to local heating.
To determine if lidocaine administered in the brachial arteries of volunteers alters the vasodilator responses to a brief forearm contraction and bolus infusions of the vasodilators acetylcholine and nitroprusside.
The overall objective of this project is to determine whether exposure of children to anesthesia is associated with neurodevelopmental abnormalities.
Sleep apnea is the most common form of sleep disordered breathing and patients with sleep apnea exhibit persistent activation of the sympathetic nervous system. Sympathoexcitation is also the final common pathway for complications in conditions like obesity, hypertension, sleep apnea, and heart failure and plays a significant role in predicting negative clinical outcomes. However, the mechanisms of sympathoexcitation with sleep apnea are poorly understood and thus make effective therapeutic approaches difficult to develop. Intermittent hypoxia (IH) has been implicated in animal models as the primary stimulus for evoking increases in sympathetic activity with recurrent apneas. The overall goal of this application is to better understand the effect of IH on sympathetic discharge patterns in humans as well as the mechanisms mediating persistent sympathoexcitation with IH.
The goal of this study is to survey the intraoperative dynamics of thrombin generation in pediatric patients ≤ 20 kg undergoing cardiac surgery.
The purpose of this study is to develop an interactive medical record timeline based on physician preferences and perceived clinical needs, to improve the chart review process for new patient encounters in the ICU.
The purpose of this study is to compare the effectiveness of pain control between a single shot interscalene brachial plexus nerve block, a continuous interscalene brachial plexus nerve block, and a local infiltration analgesia. Total shoulder arthroplasty is considered to be a major surgical procedure resulting in severe postoperative pain, especially in the first 48 hours after surgery. The use of interscalene brachial plexus nerve block remains the cornerstone for analgesia following shoulder surgery, however, there has been increasing interest in local infiltration analgesia use for total joint arthroplasty. The benefits of local infiltration analgesia within a comprehensive analgesia clinical pathway have yet to be established.
The aim of this study is to better understand providers’ attitudes, perceptions and knowledge of pharmacogenomics and to examine the impact of experiential education with providers.