Anesthesiology and Perioperative Medicine

Below are current clinical trials.

34 studies in Anesthesiology and Perioperative Medicine
(open studies only).

Filter this list of studies by location, status and more.

1. Learning More about How your Brain Works with Decreased Levels of Oxygen

   Rochester, Minn.

   The specific aim of this proposal is (1) to develop a human model of hypoxia in which cerebrovascular reactivity and cognitive function can be simultaneously measured and (2) develop pilot data in our laboratory on the relationship between cerebrovascular reactivity and cognitive function during three different hypoxic conditions with and without addition of inspired CO2 as a mechanism to maintain cerebral blood flow.

2. A Study to Assess Physician Preferences for Electronic Chart Review and Historical Information Needs for New Patient Encounters in the ICU

   Rochester, Minn.

   The purpose of this study is to develop an interactive medical record timeline based on physician preferences and perceived clinical needs, to improve the chart review process for new patient encounters in the ICU.

3. A Study to Evaluate Unintended Prolonged Opioid Use

   Rochester, Minn.

   The primary purpose of this study is to identify patient characteristics that are associated with unintended prolonged opioid use (UPUO).

4. Metabolomic Profiling of Patients Undergoing Total Knee Arthroplasty

   Jacksonville, Fla.

   The purpose of this study is to gather initial data for pain biomarker discovery in humans with correlation to clinical outcomes. Additionally, the study will test the hypothesis that the analgesic mechanism of acetaminophen in humans relies on the serotonergic and endocannabinoid system. 

5. A Study of the Impact of CVS-ICU Cardiac Arrest Efficiency Initiative on the Delay from Cardiac Arrest to Critical Resuscitation Efforts

   Rochester, Minn.

   The primary aim of this study is to determine the impact of our CVS-ICU cardiac arrest efficiency initiative on the delay from cardiac arrest to critical resuscitation efforts.

6. A Study About Comparing a New Test of Blood Clotting with Standard Tests of Blood Clotting in Patients Who are Undergoing Heart Surgery

   Rochester, Minn.

   The purpose of this study is to determine the correlation of the MCTS - CT with standard coagulation tests and coagulation factor levels.

7. A Study to Compare the ToFscan and TetraGraph During Recovery of Neuromuscular Function in the Post Anesthesia Care Unit

   Jacksonville, Fla.

   The purpose of this study is to assess the agreement and repeatability between TOF values obtained from ToFscan and TetraGraph.

8. Study to Evaluate the Effects of Vitamin B3 Derivative on Bone, Skeletal, Muscle and Metabolic Functions in Aging

   Rochester, Minn.

   The purpose of this study is to evaluate the effects of vitamin B3 derivative on bone, skeletal, muscle and metabolic functions in aging.

9. Cervical Spinal Cord Stimulation in Cerebral Vasospasm

   Jacksonville, Fla.

   The study is a non-blinded evaluation of the use of cervical spinal cord stimulation (SCS) for treatment of patients with Hunt and Hess grade 1-2 subarachnoid hemorrhage and evidence of cerebral vasospasm.

10. A Study to Analyze the Effects of Buprenorphine on Hyperalgesia in Patients with Opioid Use Disorder

    Rochester, Minn.

    The purpose of this study is to investigate the effects of buprenorphine on hyperalgesia (HP) perception in adults undergoing treatment for opioid use disorder (OUD).