Search for a doctor

Benjamin K. Wilke, M.D.

  1. Orthopedic Surgeon

Specialty Groups


  1. Jacksonville, Florida



Benjamin Wilke, M.D., is an Associate Professor and Consultant in the Department of Orthopedic Surgery at Mayo Clinic in Florida. Dr. Wilke specializes in orthopedic oncology and adult reconstruction and has special interests in hip and knee arthritis, bone and soft tissue tumors, and metastatic cancer.

He specializes in primary and revision hip and knee replacement procedures and enjoys utilizing the latest technology and advances in surgery, such as the anterior approach for total hip replacement and robotic surgery for partial and total knee replacements.

Dr. Wilke earned his bachelor's degree in science and graduated with honors and distinction from the University of Iowa in three years. He then went on to complete his Doctor of Medicine degree and graduated Cum Laude from St. Louis University School of Medicine. During his time in medical school he received the Outstanding Scholar Award and was inducted into the Alpha Omega Alpha Honor Society.

Dr. Wilke then received his orthopedic surgery training at the Mayo Clinic in Rochester, Minnesota, where he had the distinction of serving as Chief Resident. He then continued his training with a fellowship in Orthopedic Oncology at the University of Florida.

Dr. Wilke enjoys mentoring orthopedic residents and is actively involved in research. He has authored over fifty scientific publications and has contributed to multiple book chapters. He has presented both nationally and internationally. His research interests include opioid-sparing surgery, enhanced recovery after hip and knee replacement surgery, and desmoid tumors.

In his free time Dr. Wilke enjoys spending time with his family and two dogs. He is an avid reader and enjoys learning new skills.

  1. Arthritis
  2. Benign bone tumor
  3. Benign peripheral nerve tumor
  4. Bone cancer
  5. Bone metastasis
  6. Bone tumor
  7. Desmoid tumor
  8. Failed total hip replacement
  9. Failed total knee replacement
  10. Hip arthritis
  11. Infected total hip replacement
  12. Infected total knee replacement
  13. Knee arthritis
  14. Malignant peripheral nerve sheath tumors
  15. Neurofibroma
  16. Peripheral nerve tumor
  17. Sarcoma
  18. Schwannoma
  19. Soft tissue sarcoma
  20. Soft tissue tumor
  1. Bone metastasis surgery
  2. Cancer treatment
  3. Direct anterior approach hip replacement
  4. Hip fracture surgery
  5. Hip replacement
  6. Hip replacement revision
  7. Hip surgery
  8. Knee replacement
  9. Knee replacement revision
  10. Knee surgery
  11. Osseointegration procedure for amputees
  12. Partial knee replacement
  13. Peripheral nerve tumor surgery
  14. Robot-assisted knee replacement
  15. Soft tissue sarcoma surgery
  16. Surgical stabilization of metastatic bone cancer
  1. 2017
    Fellow - Orthopedic Oncology University of Florida
  2. 2016
    ResidentOrthopedic Surgery, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  3. 2011
    MDSaint Louis University
  4. 2007
    BSUniversity of Iowa


  1. 2019
    American Board of Orthopaedic Surgery

Awards and honors

  1. 2021
    Excellence in Teaching Associate Faculty AwardUniversity of Florida
  2. 2015
    Administrative Chief ResidentDepartment of Orthopedic Surgery
  3. 2011
    Donald W. Bussmann M.D. AwardSaint Louis University School of Medicine
  4. 2011
    Graduated Cum LaudeSaint Louis University School of Medicine
  5. 2010
    Most Outstanding Scholar AwardSaint Louis University School of Medicine
  6. 2010
    Alpha Omega Alpha Honor Society
  7. 2007
    Graduated with Honors and DistinctionUniversity of Iowa

Professional memberships

  1. 2020 - present
    MemberMedical Device Sterilization and Disinfection Oversight Group
  2. 2019 - 2020
    MemberSurgical Turnover and Ready Times Work Group (S.T.A.R.T.)
  3. 2018 - present
    MemberAmerican Academy of Orthopedic Surgery (AAOS)
  4. 2018 - 2019
    MemberOpioid Task Force
  5. 2016 - present
    MemberMusculoskeletal Tumor Society
  6. 2007 - 2011