Nicholas M. Wetjen, M.D.

  1. Neurosurgeon
  2. Pediatric Neurosurgeon



  1. Rochester, Minnesota



Dr. Wetjen has clinical and research interests in the following areas as well as expertise in:

  • Pediatric epilepsy surgery. Dr. Wetjen's pediatric epilepsy surgery research is directed at the investigation of imaging and EEG signatures to more precisely locate where seizures arise in the brain. In addition, he has an interest in combining imaging for use in the operating room to make surgery more accurate by developing technology for less invasive epilepsy surgery, including the use of stimulation technology for treating epilepsy.
  • Craniofacial surgery and craniosynostosis. Studies are underway in the Craniofacial Clinic to understand the relationship between craniosynostosis and gene expression, to better quantify differences in head shape results after surgery, and to develop patient-centered outcomes of success following endoscopic and open craniosynostosis surgery.
  • Fetal surgery. The Mayo Clinic Fetal Treatment Center is at the cutting edge of developing new techniques to improve outcomes related to the repair of spina bifida prior to birth. Dr. Wetjen and his team are investigating less invasive approaches to fetal surgery and improving upon spina bifida closure techniques to improve outcomes for the baby and mother.
  • Pediatric occipitocervical junction, cervical spine surgery and Chiari malformation. Dr. Wetjen's goal is to better define which patients improve following surgery by developing clinical prediction rules, to understand the natural history of pediatric cervical and occipitocervical anomalies with the timing of surgical intervention in patients with Chiari malformation, and to develop patient-centered outcomes of surgical success following Chiari surgery.
  • Pediatric skull base surgery and developmental malformations of the skull, brain and spine. Brain computer interface and limb reanimation technology is being developed for the treatment of impaired neurological function in patients with congenital and traumatic injuries of the central nervous system. Studies are ongoing to understand gait development in children with spina bifida and how early intervention with neuroprosthetic and neuroregenerative technologies may help recover function in these children.
  • Pediatric cerebrovascular surgery, moyamoya disease and arteriovenous malformations. The Mayo Clinic Children's Center has multidisciplinary experts in diseases of the blood vessels of the brain and spinal cord. Dr. Wetjen's research focuses on defining which patients benefit from early surgery and which types of imaging studies best help in making that decision.
  1. Brain AVM
  2. Chiari malformation
  3. Moyamoya disease
  4. Myelopathy
  5. Pediatric brain tumor
  6. Spina bifida
  1. Arteriovenous malformation surgery
  2. Chiari malformation surgery
  3. Epilepsy surgery
  4. Pediatric brain tumor surgery
  5. Pediatric cervical spine surgery
  • Spina bifida surgery
  • Pediatric cervical spine surgery
  • Pediatric epilepsy surgery
  • Pediatric Chiari malformation surgery
  • Pediatric brain tumor surgery
  • Moyamoya disease
  • Cranial malformations
  • Congenital spinal anomalies
  • Pediatric arteriovenous surgeries
  • Tethered cord syndrome

Rochester, Minnesota

  1. 2018
    BASIC SCIENCE MASTERSClinical and Translational Science, Programs, Mayo Graduate School, Mayo Clinic College of Medicine
  2. 2008
    Fellow - Pediatric NeurosurgeryPrimary Children's Medical Center, University of Utah
  3. 2007
    ResidentNeurologic Surgery Program, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  4. 2006
    Clinical Research Fellowship - Core Curriculum in Clinical Research CertificateSurgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health
  5. 2001
    InternshipMayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  6. 2000
    MDCarver College of Medicine, University of Iowa
  7. 1996
    BS - Majors: Chemistry and Biology ResearchLoras College


  1. 2012
    Pediatric Neurological SurgeryAmerican Board of Pediatric Neurological surgery
  2. 2011
    Neurological SurgeryAmerican Board of Neurological Surgery

Awards and honors

  1. 1997
    Best Clinical Research - Surgical Resident Research DayAwarding Organization
  2. 1996
    Honors Degree RecipientLoras College
  3. 1996
    Magna Cum LaudeLoras College
  4. 1996
    Senior AwardAmerican Institute of Chemists
  5. 1995
    Finalist, Loras College Faculty-Staff ScholarshipAwarding Organization
  6. 1994
    Award for Outstanding Achievement in Organic ChemistryAmerican Chemical Society
  7. 1994
    Division of Analytical Chemistry Undergraduate Award in Analytical ChemistryAmerican Chemical Society
  8. 1994
    Monsignor George N. Schulte ScholarshipAwarding Organization
  9. 1994
    MemberDelta Epsilon Sigma National Catholic Honor Society
  10. 1993
    Academic ScholarshipAwarding Organization
  11. 1992
    MemberAlpha Lambda Delta National Honor Society
  12. 1992
    MemberPhi Eta Sigma National Honor Society
  13. 1991
    Dean's ListAwarding Organization
  14. 1991
    Rocky Mountain Leadership ConferenceAwarding Organization
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Professional memberships

  1. 2016
    Guest ExaminerAmerican Board of Neurological Surgery
  2. 2016 - present
    Board MemberCompass to Care
  3. 2014
    FacultyUpdate in Epilepsy Surgery, Congress of Neurological Surgeons
  4. 2014 - present
    MemberPublications Committee, Western Trauma Association
  5. 2013 - present
    FellowAmerican College of Surgeons
  6. 2013 - present
    MemberFetal Myelomeningocele (fMMC) Registry Oversite Subcommittee, North America Fetal Treatment Network
  7. 2013 - present
    MemberInternational Hydrocephalus Imaging Working Group
  8. 2013 - present
    MemberTrauma Center Research Committee
  9. 2013 - present
    MemberWestern Trauma Association
  10. 2012
    Organizing MemberNorth America Fetal Treatment Network
  11. 2012
    LiaisonNorth America Fetal Treatment Network
  12. 2012 - present
    MemberExecutive Operating Committee, Mayo Clinic Children's Center
  13. 2012 - present
    MemberAmerican Society of Pediatric Neurological Surgery
  14. 2011
    Associate MemberAmerican Society of Pediatric Neurological Surgery
  15. 2011 - present
    DirectorMarketing, Mayo Clinic Children's Center
  16. 2011 - present
    MemberAmerican Association for the Advancement of Science
  17. 2011 - present
    FellowSection on Neurological Surgery, American Academy of Pediatrics
  18. 2011 - present
    MemberNational Catholic Medical Association
  19. 2011 - present
    FellowAmerican Association of Neurological Surgeons
  20. 2010 - present
    SpeakerMorbidity and Mortality, Department of Neurologic Surgery
  21. 2010 - present
    DirectorMorbidity and Mortality, Department of Neurologic Surgery
  22. 2010 - present
    MemberCore Curriculum Development, Department of Neurologic Surgery
  23. 2009 - present
    MemberPediatric Neuro-oncology Work Group
  24. 2009 - present
    MemberAANS/CNS Tumor Section, American Association of Neurological Surgeons
  25. 2009 - present
    MemberAANS/CNS Neurotrauma and Critical Care Section, American Association of Neurological Surgeons
  26. 2008 - 2009
    MemberAmerican Medical Association
  27. 2008 - present
    Doctors Mayo Society, Mayo Clinic Alumni Association, Mayo Clinic College of Medicine and Science
  28. 2008 - present
    MemberPediatric Trauma Committee
  29. 2008 - present
    MemberEducation Committee, Department of Neurologic Surgery
  30. 2008 - present
    MemberCongress of Neurological Surgeons
  31. 2008 - present
    MemberAmerican Epilepsy Society
  32. 2008 - present
    MemberAOSPINE International
  33. 2008 - present
    MemberChildrens' Oncology Group
  34. 2008 - present
    MemberInternational Society for Pediatric Neurosurgery
  35. 2008 - present
    MemberAANS/CNS Section for Pediatric Neurosurgery, American Association of Neurological Surgeons
  36. 2008 - present
    MemberSigma Xi, The Scientific Research Society
  37. 2007 - present
    MemberPediatric Craniocervical Society
  38. 2007 - present
    MemberSociety of Neuro-oncology
  39. 2006 - present
    MemberNatural Disaster Committee, World Federation of Neurological Societies
  40. 2000 - 2007
    Resident MemberAmerican Association of Neurological Surgeons
  41. 2000 - 2007
    Resident MemberCongress of Neurological Surgeons
  42. 2000 - present
    MemberMinnesota Neurosurgical Society
  43. 1998 - 2000
    TutorAnatomy and Medical Neuroscience, Carver College of Medicine, University of Iowa
  44. 1996 - 2000
    MemberSurgical Interest Society, Carver College of Medicine, University of Iowa
  45. 1996 - 2000
    MemberMedical Student Research Club, Carver College of Medicine, University of Iowa
  46. 1994 - 1996
    MemberSigma Xi, The Scientific Research Society
  47. 1993 - 1996
    President and FounderHealth Science Club, Loras College
  48. 1991 - 1992
    Associate SenatorAssociated Students of Colorado State University, Colorado State University
  49. 1991 - 1992
    MemberPremedica, Colorado State University
  50. 1991 - 1992
    Founding MemberSigma Pi Fraternity, Colorado State University
    MemberCollege of Natural Sciences, Colorado State University
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