Daniel B. Saris, M.D., Ph.D.

  1. Orthopedic Surgeon
  2. Sports Medicine Specialist

Publications

  1. Hevesi M, Sanders TL, Pareek A, Milbrandt TA, Levy BA, Stuart MJ, Saris DBF, Krych AJ. Osteochondritis Dissecans in the Knee of Skeletally Immature Patients: Rates of Persistent Pain, Osteoarthritis, and Arthroplasty at Mean 14-Years' Follow-Up. Cartilage. 2020 Jul; 11 (3):291-299 Epub 2018 July 12
    View PubMed
  2. Krych AJ, Wu IT, Desai VS, Kennedy NI, Littrell LA, Collins MS, Saris DBF, Stuart MJ. Osteomeniscal Impact Edema (OMIE): Description of a Distinct MRI Finding in Displaced Flap Tears of the Medial Meniscus, with Comparison to Posterior Root Tears. J Knee Surg. 2020 Jul; 33 (7):659-665 Epub 2019 Mar 28
    View PubMed
  3. Pareek A, Parkes CW, Bernard C, Camp CL, Saris DBF, Stuart MJ, Krych AJ. Spontaneous Osteonecrosis/Subchondral Insufficiency Fractures of the Knee: High Rates of Conversion to Surgical Treatment and Arthroplasty. J Bone Joint Surg Am. 2020 May 6; 102 (9):821-829
    View PubMed
  4. Bloembergen CH, van de Graaf VA, Virgile A, Willigenburg NW, Noorduyn JCA, Saris DB, Harris I, Poolman RW. Infographic. Can even experienced orthopaedic surgeons predict who will benefit from surgery when patients present with degenerative meniscal tears? A survey of 194 orthopaedic surgeons who made 3880 predictions. Br J Sports Med. 2020 May; 54 (9):556-557 Epub 2019 Oct 25
    View PubMed
  5. Zarringam D, Saris DBF, Bekkers JEJ. Identification of early prognostic factors for knee and hip arthroplasty; a long-term follow-up of the CHECK cohort. J Orthop. 2020 May-Jun; 19:41-45 Epub 2019 Nov 06
    View PubMed
  6. van de Graaf VA, van Dongen JM, Willigenburg NW, Noorduyn JCA, Butter IK, de Gast A, Saris DBF, van Tulder MW, Poolman RW, ESCAPE Research Group. How do the costs of physical therapy and arthroscopic partial meniscectomy compare? A trial-based economic evaluation of two treatments in patients with meniscal tears alongside the ESCAPE study. Br J Sports Med. 2020 May; 54 (9):538-545 Epub 2019 June 21
    View PubMed
  7. Pareek A, Parkes CW, Bernard C, Camp CL, Saris DBF, Stuart MJ, Krych AJ. Spontaneous Osteonecrosis/Subchondral Insufficiency Fractures of the Knee: High Rates of Conversion to Surgical Treatment and Arthroplasty. J Bone Joint Surg Am. 2020 Apr 2 Epub 2020 Apr 02
    View PubMed
  8. van de Graaf VA, Bloembergen MD, Willigenburg NW, Noorduyn MSc, Saris DB, Harris IA, Poolman RW, ESCAPE Research Group. Can even experienced orthopaedic surgeons predict who will benefit from surgery when patients present with degenerative meniscal tears? A survey of 194 orthopaedic surgeons who made 3880 predictions. Br J Sports Med. 2020 Mar; 54 (6):354-359 Epub 2019 Aug 01
    View PubMed
  9. Merkely G, Farr J, Saris D, Lattermann C. Cartilage surface treatment: factors affecting success and failure mechanisms Operative Techniques In Sports Medicine. 2020 Mar; 28 (1):150711
  10. Bernard CD, Kennedy NI, Tagliero AJ, Camp CL, Saris DBF, Levy BA, Stuart MJ, Krych AJ. Medial Meniscus Posterior Root Tear Treatment: A Matched Cohort Comparison of Nonoperative Management, Partial Meniscectomy, and Repair. Am J Sports Med. 2020 Jan; 48 (1):128-132 Epub 2019 Nov 25
    View PubMed
  11. Hevesi M, LaPrade M, Saris DBF, Krych AJ. Stem Cell Treatment for Ligament Repair and Reconstruction. Curr Rev Musculoskelet Med. 2019 Dec; 12 (4):446-450
    View PubMed
  12. Denbeigh JM, Hevesi M, Paggi CA, Resch ZT, Bagheri L, Mara K, Arani A, Zhang C, Larson AN, Saris DBF, Krych AJ, van Wijnen AJ. Modernizing Storage Conditions for Fresh Osteochondral Allografts by Optimizing Viability at Physiologic Temperatures and Conditions. Cartilage. 2019 Nov 28; 1947603519888798 [Epub ahead of print]
    View PubMed
  13. Pareek A, Parkes CW, Bernard CD, Abdel MP, Saris DBF, Krych AJ. The SIFK score: a validated predictive model for arthroplasty progression after subchondral insufficiency fractures of the knee. Knee Surg Sports Traumatol Arthrosc. 2019 Nov 20 [Epub ahead of print]
    View PubMed
  14. Hevesi M, Denbeigh JM, Paggi CA, Galeano-Garces C, Bagheri L, Larson AN, Stuart MJ, Saris DBF, van Wijnen AJ, Krych AJ. Fresh Osteochondral Allograft Transplantation in the Knee: A Viability and Histologic Analysis for Optimizing Graft Viability and Expanding Existing Standard Processed Graft Resources Using a Living Donor Cartilage Program. Cartilage. 2019 Oct 16; 1947603519880330 [Epub ahead of print]
    View PubMed
  15. Leland DP, Bernard CD, Camp CL, Nakamura N, Saris DBF, Krych AJ. Does Internal Fixation for Unstable Osteochondritis Dissecans of the Skeletally Mature Knee Work? A Systematic Review. Arthroscopy. 2019 Aug; 35 (8):2512-2522
    View PubMed
  16. Dijkstra K, Huitsing RPJ, Custers RJH, Kouwenhoven JWM, Bleys RLAW, Vonk LA, Saris DBF. Preclinical Feasibility of the Bio-Airbrush for Arthroscopic Cell-Based Cartilage Repair. Tissue Eng Part C Methods. 2019 Jul; 25 (7):379-388
    View PubMed
  17. Zarringam D, Saris DBF, Bekkers JEJ. The Value of SPECT/CT for Knee Osteoarthritis: A Systematic Review. Cartilage. 2019 Jun 16; 1947603519855776 Epub 2019 June 16
    View PubMed
  18. Melugin HP, Bernard CD, Camp CL, Saris DBF, Krych AJ. Bipolar Cartilage Lesions of the Knee: A Systematic Review of Techniques, Outcomes, and Complications. Cartilage. 2019 Jun 16; 1947603519855761 Epub 2019 June 16
    View PubMed
  19. Melugin HP, Bernard CD, Camp CL, Stuart MJ, Saris DBF, Nakamura N, Krych AJ. Tibial Plateau Cartilage Lesions: A Systematic Review of Techniques, Outcomes, and Complications. Cartilage. 2019 Jun 16; 1947603519855767 Epub 2019 June 16
    View PubMed
  20. Hevesi M, Krych AJ, Saris DBF. Treatment of Cartilage Defects With the Matrix-Induced Autologous Chondrocyte Implantation Cookie Cutter Technique. Arthrosc Tech. 2019 Jun; 8 (6):e591-e596 Epub 2019 May 16
    View PubMed
  21. Hagmeijer MH, Hevesi M, Desai VS, Sanders TL, Camp CL, Hewett TE, Stuart MJ, Saris DBF, Krych AJ. Secondary Meniscal Tears in Patients With Anterior Cruciate Ligament Injury: Relationship Among Operative Management, Osteoarthritis, and Arthroplasty at 18-Year Mean Follow-up. Am J Sports Med. 2019 Jun; 47 (7):1583-1590
    View PubMed
  22. Murray IR, Chahla J, Safran MR, Krych AJ, Saris DBF, Caplan AI, LaPrade RF, Cell Therapies Communication Expert Group. International Expert Consensus on a Cell Therapy Communication Tool: DOSES. J Bone Joint Surg Am 2019 May 15; 101 (10):904-911
    View PubMed
  23. Hevesi M, Crispim JF, Paggi CA, Dudakovic A, van Genechten W, Hewett T, Kakar S, Krych AJ, van Wijnen AJ, Saris DBF. A Versatile Protocol for Studying Anterior Cruciate Ligament Reconstruction in a Rabbit Model. Tissue Eng Part C Methods. 2019 Apr; 25 (4):191-196
    View PubMed
  24. Hagmeijer MH, Kennedy NI, Tagliero AJ, Levy BA, Stuart MJ, Saris DBF, Dahm DL, Krych AJ. Long-term Results After Repair of Isolated Meniscal Tears Among Patients Aged 18 Years and Younger: An 18-Year Follow-up Study. Am J Sports Med. 2019 Mar; 47 (4):799-806 Epub 2019 Feb 25
    View PubMed
  25. Hevesi M, Paradise CR, Paggi CA, Galeano-Garces C, Dudakovic A, Karperien M, Kakar S, Hewett T, Krych A, van Wijnen AJ, Saris DBF. Defining the baseline transcriptional fingerprint of rabbit hamstring autograft Gene Reports. 1/18/2019.
  26. de Windt TS, Niemansburg SL, Vonk LA, van Delden JM, Roes KCB, Dhert WJA, Saris DBF, Bredenoord AL. Ethics in musculoskeletal regenerative medicine; guidance in choosing the appropriate comparator in clinical trials. Osteoarthritis Cartilage. 2019 Jan; 27 (1):34-40 Epub 2018 Sept 20
    View PubMed
  27. Hagmeijer MH, Vonk LA, Kouwenhoven JW, Custers RJH, Bleys RL, Krych AJ, Saris DBF. Surgical Feasibility of a One-Stage Cell-Based Arthroscopic Procedure for Meniscus Regeneration: A Cadaveric Study. Tissue Eng Part C Methods. 2018 Dec; 24 (12):688-696
    View PubMed
  28. van de Graaf VA, Noorduyn JCA, Willigenburg NW, Butter IK, de Gast A, Mol BW, Saris DBF, Twisk JWR, Poolman RW, ESCAPE Research Group. Effect of Early Surgery vs Physical Therapy on Knee Function Among Patients With Nonobstructive Meniscal Tears: The ESCAPE Randomized Clinical Trial. JAMA. 2018 Oct 2; 320 (13):1328-1337
    View PubMed
  29. Hevesi M, Hartigan DE, Wu IT, Wyles CC, Desai VS, van Wijnen AJ, Saris DBF, Levy BA, Krych AJ. The Rapidly Assessed Predictor of Intraoperative Damage (RAPID) Score: An In-Clinic Predictive Model for High-Grade Acetabular Chondrolabral Disruption. Orthop J Sports Med. 2018 Oct; 6 (10):2325967118799068 Epub 2018 Oct 03
    View PubMed
  30. Paradise CR, Galeano-Garces C, Galeano-Garces D, Dudakovic A, Milbrandt TA, Saris DBF, Krych AJ, Karperien M, Ferguson GB, Evseenko D, Riester SM, van Wijnen AJ, Larson AN. Molecular characterization of physis tissue by RNA sequencing. Gene. 2018 Aug 20; 668:87-96 Epub 2018 May 25
    View PubMed
  31. Wu IT, Custers RJH, Desai VS, Pareek A, Stuart MJ, Saris DBF, Krych AJ. Internal Fixation of Unstable Osteochondritis Dissecans: Do Open Growth Plates Improve Healing Rate? Am J Sports Med. 2018 Aug; 46 (10):2394-2401 Epub 2018 July 11
    View PubMed
  32. Brinkhof S, Nizak R, Khlebnikov V, Prompers JJ, Klomp DWJ, Saris DBF. Detection of early cartilage damage: feasibility and potential of gagCEST imaging at 7T. Eur Radiol. 2018 Jul; 28 (7):2874-2881 Epub 2018 Jan 30
    View PubMed
  33. Krych AJ, Hevesi M, Desai VS, Camp CL, Stuart MJ, Saris DBF. Learning From Failure in Cartilage Repair Surgery: An Analysis of the Mode of Failure of Primary Procedures in Consecutive Cases at a Tertiary Referral Center. Orthop J Sports Med. 2018 May; 6 (5):2325967118773041 Epub 2018 May 17
    View PubMed
  34. Brittberg M, Recker D, Ilgenfritz J, Saris DBF, SUMMIT Extension Study Group. Matrix-Applied Characterized Autologous Cultured Chondrocytes Versus Microfracture: Five-Year Follow-up of a Prospective Randomized Trial. Am J Sports Med. 2018 May; 46 (6):1343-1351 Epub 2018 Mar 22
    View PubMed
  35. Krych AJ, Wu IT, Desai VS, Murthy NS, Collins MS, Saris DBF, Levy BA, Stuart MJ. High Rate of Missed Lateral Meniscus Posterior Root Tears on Preoperative Magnetic Resonance Imaging. Orthop J Sports Med. 2018 Apr; 6 (4):2325967118765722 Epub 2018 Apr 09
    View PubMed
  36. Ghebes CA, Groen N, Cheuk YC, Fu SC, Fernandes HM, Saris DBF. Muscle-Secreted Factors Improve Anterior Cruciate Ligament Graft Healing: An In Vitro and In Vivo Analysis. Tissue Eng Part A. 2018 Feb; 24 (3-4):322-334 Epub 2017 July 05
    View PubMed
  37. Vonk LA, van Dooremalen SFJ, Liv N, Klumperman J, Coffer PJ, Saris DBF, Lorenowicz MJ. Mesenchymal Stromal/stem Cell-derived Extracellular Vesicles Promote Human Cartilage Regeneration In Vitro. Theranostics. 2018; 8 (4):906-920 Epub 2018 Jan 01
    View PubMed
  38. Saris DBF, de Windt TS, Vonk LA, Krych AJ, Terzic A. Regenerative Musculoskeletal Care: Ensuring Practice Implementation. Clin Pharmacol Ther. 2018 Jan; 103 (1):50-53 Epub 2017 Oct 16
    View PubMed
  39. Hendriks J, Stojanovic I, Schasfoort RBM, Saris D, Karperien M. Nanoparticle enhancement cascade for sensitive multiplex measurements of biomarkers in complex fluids with surface pasmon resonance imaging Anal Chem. 2018; 90:6563-6571.
  40. Pareek A, Sanders TL, Wu IT, Larson DR, Saris DBF, Krych AJ. Incidence of symptomatic osteochondritis dissecans lesions of the knee: a population-based study in Olmsted County. Osteoarthritis Cartilage. 2017 Oct; 25 (10):1663-1671 Epub 2017 July 12
    View PubMed
  41. Zhao X, Hwang NS, Bichara DA, Saris DB, Malda J, Vacanti JP, Pomerantseva I, Sundback CA, Langer R, Anderson DG, Randolph MA. Chondrogenesis by bone marrow-derived mesenchymal stem cells grown in chondrocyte-conditioned medium for auricular reconstruction. J Tissue Eng Regen Med. 2017 Oct; 11 (10):2763-2773 Epub 2016 June 03
    View PubMed
  42. de Windt TS, Sorel JC, Vonk LA, Kip MMA, Ijzerman MJ, Saris DBF. Early health economic modelling of single-stage cartilage repair. Guiding implementation of technologies in regenerative medicine. J Tissue Eng Regen Med. 2017 Oct; 11 (10):2950-2959 Epub 2016 July 12
    View PubMed
  43. Mouser VHM, Levato R, Bonassar LJ, D'Lima DD, Grande DA, Klein TJ, Saris DBF, Zenobi-Wong M, Gawlitta D, Malda J. Three-Dimensional Bioprinting and Its Potential in the Field of Articular Cartilage Regeneration. Cartilage. 2017 Oct; 8 (4):327-340 Epub 2016 Sept 01
    View PubMed
  44. Woodmass JM, Melugin HP, Wu IT, Saris DBF, Stuart MJ, Krych AJ. Viable Osteochondral Allograft for the Treatment of a Full-Thickness Cartilage Defect of the Patella. Arthrosc Tech. 2017 Oct; 6 (5):e1661-e1665 Epub 2017 Sept 25
    View PubMed
  45. Dijkstra K, Hendriks J, Karperien M, Vonk LA, Saris DBF. Arthroscopic Airbrush-Assisted Cell Spraying for Cartilage Repair: Design, Development, and Characterization of Custom-Made Arthroscopic Spray Nozzles. Tissue Eng Part C Methods. 2017 Sep; 23 (9):505-515 Epub 2017 Aug 08
    View PubMed
  46. de Windt TS, Vonk LA, Slaper-Cortenbach ICM, Nizak R, van Rijen MHP, Saris DBF. Allogeneic MSCs and Recycled Autologous Chondrons Mixed in a One-Stage Cartilage Cell Transplantion: A First-in-Man Trial in 35 Patients. Stem Cells. 2017 Aug; 35 (8):1984-1993 Epub 2017 June 23
    View PubMed
  47. Woodmass JM, Johnson JD, Wu IT, Saris DBF, Stuart MJ, Krych AJ. Horizontal Cleavage Meniscus Tear Treated With All-inside Circumferential Compression Stitches. Arthrosc Tech. 2017 Aug; 6 (4):e1329-e1333 Epub 2017 Aug 14
    View PubMed
  48. van Gorp JS, Nizak R, Bouwman JG, Saris DBF, Seevinck PR. Multispectral 3D phase-encoded turbo spin-echo for imaging near metal: Limitations and possibilities demonstrated by simulations and phantom experiments. Magn Reson Imaging. 2017 Jun; 39:31-43 Epub 2017 Jan 25
    View PubMed
  49. van der Linde JA, van Kampen DA, van Beers LWAH, van Deurzen DFP, Saris DBF, Terwee CB. The Responsiveness and Minimal Important Change of the Western Ontario Shoulder Instability Index and Oxford Shoulder Instability Score. J Orthop Sports Phys Ther. 2017 Jun; 47 (6):402-410 Epub 2017 May 12
    View PubMed
  50. Nizak R, Bekkers J, de Jong PA, Witkamp T, Luijkx T, Saris D. Osteochondral lesion depth on MRI can help predict the need for a sandwich procedure. Eur J Radiol. 2017 May; 90:245-249 Epub 2017 Mar 18
    View PubMed
  51. Crispim J, Fernandes HAM, Fu SC, Lee YW, Jonkheijm P, Saris DBF. TGF-beta1 activation in human hamstring cells through growth factor binding peptides on polycaprolactone surfaces. Acta Biomater. 2017 Apr 15; 53:165-178 Epub 2017 Jan 26
    View PubMed
  52. Vazao H, Rosa S, Barata T, Costa R, Pitrez PR, Honorio I, de Vries MR, Papatsenko D, Benedito R, Saris D, Khademhosseini A, Quax PH, Pereira CF, Mercader N, Fernandes H, Ferreira L. High-throughput identification of small molecules that affect human embryonic vascular development. Proc Natl Acad Sci U S A. 2017 Apr 11; 114 (15):E3022-E3031 Epub 2017 Mar 27
    View PubMed
  53. Korpershoek JV, de Windt TS, Hagmeijer MH, Vonk LA, Saris DB. Cell-Based Meniscus Repair and Regeneration: At the Brink of Clinical Translation?: A Systematic Review of Preclinical Studies. Orthop J Sports Med. 2017 Feb; 5 (2):2325967117690131 Epub 2017 Feb 21
    View PubMed
  54. de Windt TS, Vonk LA, Slaper-Cortenbach IC, van den Broek MP, Nizak R, van Rijen MH, de Weger RA, Dhert WJ, Saris DB. Allogeneic Mesenchymal Stem Cells Stimulate Cartilage Regeneration and Are Safe for Single-Stage Cartilage Repair in Humans upon Mixture with Recycled Autologous Chondrons. Stem Cells. 2017 Jan; 35 (1):256-264 Epub 2016 Aug 29
    View PubMed
  55. Ghebes CA, van Lente J, Post JN, Saris DB, Fernandes H. High-Throughput Screening Assay Identifies Small Molecules Capable of Modulating the BMP-2 and TGF-beta1 Signaling Pathway. SLAS Discov. 2017 Jan; 22 (1):40-50 Epub 2016 Sept 27
    View PubMed
  56. van de Graaf VA, Scholtes VA, Wolterbeek N, Noorduyn JC, Neeter C, van Tulder MW, Saris DB, de Gast A, Poolman RW, Escape Research Group. Cost-effectiveness of Early Surgery versus Conservative Treatment with Optional Delayed Meniscectomy for Patients over 45 years with non-obstructive meniscal tears (ESCAPE study): protocol of a randomised controlled trial. BMJ Open. 2016 Dec 21; 6 (12):e014381
    View PubMed
  57. Ghebes CA, Braham MV, Zeegers AV, Renard AJ, Fernandes H, Saris DB. Means of enhancing bone fracture healing: optimal cell source, isolation methods and acoustic stimulation. BMC Biotechnol. 2016 Dec 12; 16 (1):89
    View PubMed
  58. van de Graaf VA, Wolterbeek N, Mutsaerts EL, Scholtes VA, Saris DB, de Gast A, Poolman RW. Arthroscopic Partial Meniscectomy or Conservative Treatment for Nonobstructive Meniscal Tears: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Arthroscopy. 2016 Sep; 32 (9):1855-1865.e4 Epub 2016 July 27
    View PubMed
  59. Mok SW, Nizak R, Fu SC, Ho, Qin L, Saris, Chan KM, Malda J. From the printer: Potential of three-dimensional printing for orthopaedic applications J Orthop Trans. 2016; 6:42-49.
  60. Zhao X, Papadopoulos A, Ibusuki S, Bichara DA, Saris DB, Malda J, Anseth KS, Gill TJ, Randolph MA. Articular cartilage generation applying PEG-LA-DM/PEGDM copolymer hydrogels. BMC Musculoskelet Disord. 2016 Jun 3; 17:245 Epub 2016 June 03
    View PubMed
  61. Wiegant K, Beekhuizen M, Mastbergen SC, Kuchuk NO, Barten-van Rijbroek AD, Custers RJ, Saris DB, Creemers LB, Lafeber FP. Early evolving joint degeneration by cartilage trauma is primarily mechanically controlled. Knee. 2016 Jun; 23 (3):487-94 Epub 2016 Feb 11
    View PubMed
  62. Ekwueme EC, Shah JV, Mohiuddin M, Ghebes CA, Crispim JF, Saris DB, Fernandes HA, Freeman JW. Cross-Talk Between Human Tenocytes and Bone Marrow Stromal Cells Potentiates Extracellular Matrix Remodeling In Vitro. J Cell Biochem. 2016 Mar; 117 (3):684-93 Epub 2015 Sept 29
    View PubMed
  63. Martin I, Ireland H, Baldomero H, Dominici M, Saris DB, Passweg J. The Survey on Cellular and Engineered Tissue Therapies in Europe in 2013. Tissue Eng Part A. 2016 Jan; 22 (1-2):5-16
    View PubMed
  64. de Windt TS, Saris DB, Slaper-Cortenbach IC, van Rijen MH, Gawlitta D, Creemers LB, de Weger RA, Dhert WJ, Vonk LA. Direct Cell-Cell Contact with Chondrocytes Is a Key Mechanism in Multipotent Mesenchymal Stromal Cell-Mediated Chondrogenesis. Tissue Eng Part A. 2015 Oct; 21 (19-20):2536-47 Epub 2015 Aug 12
    View PubMed
  65. Hendriks J, Willem Visser C, Henke S, Leijten J, Saris DB, Sun C, Lohse D, Karperien M. Optimizing cell viability in droplet-based cell deposition. Sci Rep. 2015 Jun 11; 5:11304 Epub 2015 June 11
    View PubMed
  66. Vonk LA, de Windt TS, Slaper-Cortenbach IC, Saris DB. Autologous, allogeneic, induced pluripotent stem cell or a combination stem cell therapy? Where are we headed in cartilage repair and why: a concise review. Stem Cell Res Ther. 2015 May 15; 6:94
    View PubMed
  67. Rutgers M, Creemers LB, Auw Yang KG, Raijmakers NJ, Dhert WJ, Saris DB. Osteoarthritis treatment using autologous conditioned serum after placebo. Acta Orthop. 2015 Feb; 86 (1):114-8 Epub 2014 Aug 20
    View PubMed
  68. de Windt TS, Vonk LA, Buskermolen JK, Visser J, Karperien M, Bleys RL, Dhert WJ, Saris DB. Arthroscopic airbrush assisted cell implantation for cartilage repair in the knee: a controlled laboratory and human cadaveric study. Osteoarthritis Cartilage. 2015 Jan; 23 (1):143-50 Epub 2014 Sept 18
    View PubMed
  69. van Geene AR, Saris DB, Custers RJ. [Pain following primary total knee replacement: causes, diagnosis and treatment]. Ned Tijdschr Geneeskd. 2015; 159:A8445
    View PubMed
  70. Vonk LA, de Windt TS, Kragten AH, Beekhuizen M, Mastbergen SC, Dhert WJ, Lafeber FP, Creemers LB, Saris DB. Enhanced cell-induced articular cartilage regeneration by chondrons; the influence of joint damage and harvest site. Osteoarthritis Cartilage. 2014 Nov; 22 (11):1910-7 Epub 2014 Aug 20
    View PubMed
  71. Benders KE, Boot W, Cokelaere SM, Van Weeren PR, Gawlitta D, Bergman HJ, Saris DB, Dhert WJ, Malda J. Multipotent Stromal Cells Outperform Chondrocytes on Cartilage-Derived Matrix Scaffolds. Cartilage. 2014 Oct; 5 (4):221-30
    View PubMed
  72. Tsuchida AI, Beekhuizen M, 't Hart MC, Radstake TR, Dhert WJ, Saris DB, van Osch GJ, Creemers LB. Cytokine profiles in the joint depend on pathology, but are different between synovial fluid, cartilage tissue and cultured chondrocytes. Arthritis Res Ther. 2014 Sep 26; 16 (5):441 Epub 2014 Sept 26
    View PubMed
  73. Stenberg J, de Windt TS, Synnergren J, Hynsjo L, van der Lee J, Saris DB, Brittberg M, Peterson L, Lindahl A. Clinical Outcome 3 Years After Autologous Chondrocyte Implantation Does Not Correlate With the Expression of a Predefined Gene Marker Set in Chondrocytes Prior to Implantation but Is Associated With Critical Signaling Pathways. Orthop J Sports Med. 2014 Sep; 2 (9):2325967114550781 Epub 2014 Sept 24
    View PubMed
  74. Saris D, Price A, Widuchowski W, Bertrand-Marchand M, Caron J, Drogset JO, Emans P, Podskubka A, Tsuchida A, Kili S, Levine D, Brittberg M, SUMMIT study group. Matrix-Applied Characterized Autologous Cultured Chondrocytes Versus Microfracture: Two-Year Follow-up of a Prospective Randomized Trial. Am J Sports Med. 2014 Jun; 42 (6):1384-94 Epub 2014 Apr 08
    View PubMed
  75. de Windt TS, Hendriks JA, Zhao X, Vonk LA, Creemers LB, Dhert WJ, Randolph MA, Saris DB. Concise review: unraveling stem cell cocultures in regenerative medicine: which cell interactions steer cartilage regeneration and how? Stem Cells Transl Med. 2014 Jun; 3 (6):723-33 Epub 2014 Apr 24
    View PubMed
  76. Cucchiarini M, Madry H, Guilak F, Saris DB, Stoddart MJ, Koon Wong M, Roughley P. A vision on the future of articular cartilage repair. Eur Cell Mater. 2014 May 6; 27:12-6 Epub 2014 May 06
    View PubMed
  77. Bekkers JE, Saris DB, Tsuchida AI, van Rijen MH, Dhert WJ, Creemers LB. Chondrogenic potential of articular chondrocytes depends on their original location. Tissue Eng Part A. 2014 Feb; 20 (3-4):663-71 Epub 2013 Nov 14
    View PubMed
  78. Vonk LA, Kragten AH, Dhert WJ, Saris DB, Creemers LB. Overexpression of hsa-miR-148a promotes cartilage production and inhibits cartilage degradation by osteoarthritic chondrocytes. Osteoarthritis Cartilage. 2014 Jan; 22 (1):145-53 Epub 2013 Nov 21
    View PubMed
  79. Saris D. SP0121 Joint Homeostasis: Limitations and Advantages for Cartilage Repair in Oa. Annals of the Rheumatic Diseases. 2014; 73:32-33.
  80. Beekhuizen M, van Osch GJ, Bot AG, Hoekstra MC, Saris DB, Dhert WJ, Creemers LB. Inhibition of oncostatin M in osteoarthritic synovial fluid enhances GAG production in osteoarthritic cartilage repair. Eur Cell Mater. 2013 Sep 11; 26:80-90; discussion 90 Epub 2013 Sept 11
    View PubMed
  81. Bekkers JE, Tsuchida AI, van Rijen MH, Vonk LA, Dhert WJ, Creemers LB, Saris DB. Single-stage cell-based cartilage regeneration using a combination of chondrons and mesenchymal stromal cells: comparison with microfracture. Am J Sports Med. 2013 Sep; 41 (9):2158-66 Epub 2013 July 05
    View PubMed
  82. Tsuchida AI, Bekkers JE, Beekhuizen M, Vonk LA, Dhert WJ, Saris DB, Creemers LB. Pronounced biomaterial dependency in cartilage regeneration using nonexpanded compared with expanded chondrocytes. Regen Med. 2013 Sep; 8 (5):583-95
    View PubMed
  83. de Windt TS, Welsch GH, Brittberg M, Vonk LA, Marlovits S, Trattnig S, Saris DB. Is magnetic resonance imaging reliable in predicting clinical outcome after articular cartilage repair of the knee? A systematic review and meta-analysis. Am J Sports Med. 2013 Jul; 41 (7):1695-702 Epub 2013 Jan 30
    View PubMed
  84. Bekkers JE, Creemers LB, Tsuchida AI, van Rijen MH, Custers RJ, Dhert WJ, Saris DB. One-stage focal cartilage defect treatment with bone marrow mononuclear cells and chondrocytes leads to better macroscopic cartilage regeneration compared to microfracture in goats. Osteoarthritis Cartilage. 2013 Jul; 21 (7):950-6 Epub 2013 Apr 09
    View PubMed
  85. Bekkers JE, Bartels LW, Benink RJ, Tsuchida AI, Vincken KL, Dhert WJ, Creemers LB, Saris DB. Delayed gadolinium enhanced MRI of cartilage (dGEMRIC) can be effectively applied for longitudinal cohort evaluation of articular cartilage regeneration. Osteoarthritis Cartilage. 2013 Jul; 21 (7):943-9 Epub 2013 Apr 09
    View PubMed
  86. Beekhuizen M, Gierman LM, van Spil WE, Van Osch GJ, Huizinga TW, Saris DB, Creemers LB, Zuurmond AM. An explorative study comparing levels of soluble mediators in control and osteoarthritic synovial fluid. Osteoarthritis Cartilage. 2013 Jul; 21 (7):918-22 Epub 2013 Apr 15
    View PubMed
  87. de Windt TS, Vonk LA, Brittberg M, Saris DB. Treatment and Prevention of (Early) Osteoarthritis Using Articular Cartilage Repair-Fact or Fiction? A Systematic Review. Cartilage. 2013 Jul; 4 (3 Suppl):5S-12S
    View PubMed
  88. Thakkar S, Ghebes CA, Ahmed M, Kelder C, van Blitterswijk CA, Saris D, Fernandes HA, Moroni L. Mesenchymal stromal cell-derived extracellular matrix influences gene expression of chondrocytes. Biofabrication. 2013 Jun; 5 (2):025003 Epub 2013 Feb 27
    View PubMed
  89. Bekkers JE, Bartels LW, Vincken KL, Dhert WJ, Creemers LB, Saris DB. Articular cartilage evaluation after TruFit plug implantation analyzed by delayed gadolinium-enhanced MRI of cartilage (dGEMRIC). Am J Sports Med. 2013 Jun; 41 (6):1290-5 Epub 2013 Apr 12
    View PubMed
  90. Mastbergen SC, Saris DB, Lafeber FP. Functional articular cartilage repair: here, near, or is the best approach not yet clear? Nat Rev Rheumatol. 2013 May; 9 (5):277-90 Epub 2013 Mar 19
    View PubMed
  91. Doorn J, Fernandes HA, Le BQ, van de Peppel J, van Leeuwen JP, De Vries MR, Aref Z, Quax PH, Myklebost O, Saris DB, van Blitterswijk CA, de Boer J. A small molecule approach to engineering vascularized tissue. Biomaterials. 2013 Apr; 34 (12):3053-63 Epub 2013 Jan 29
    View PubMed
  92. Benders KE, van Weeren PR, Badylak SF, Saris DB, Dhert WJ, Malda J. Extracellular matrix scaffolds for cartilage and bone regeneration. Trends Biotechnol. 2013 Mar; 31 (3):169-76 Epub 2013 Jan 05
    View PubMed
  93. Saris DBF. Cell therapy, biomaterials and other options may enhance cartilage repair. Orthopaedics Today Europe. 2013.
  94. Rutgers M, Saris DB, Vonk LA, van Rijen MH, Akrum V, Langeveld D, van Boxtel A, Dhert WJ, Creemers LB. Effect of collagen type I or type II on chondrogenesis by cultured human articular chondrocytes. Tissue Eng Part A. 2013 Jan; 19 (1-2):59-65 Epub 2012 Sept 13
    View PubMed
  95. Tsuchida AI, Beekhuizen M, Rutgers M, van Osch GJ, Bekkers JE, Bot AG, Geurts B, Dhert WJ, Saris DB, Creemers LB. Interleukin-6 is elevated in synovial fluid of patients with focal cartilage defects and stimulates cartilage matrix production in an in vitro regeneration model. Arthritis Res Ther. 2012 Dec 3; 14 (6):R262 Epub 2012 Dec 03
    View PubMed
  96. de Windt TS, Concaro S, Lindahl A, Saris DB, Brittberg M. Strategies for patient profiling in articular cartilage repair of the knee: a prospective cohort of patients treated by one experienced cartilage surgeon. Knee Surg Sports Traumatol Arthrosc. 2012 Nov; 20 (11):2225-32 Epub 2012 Jan 14
    View PubMed
  97. Martin I, Baldomero H, Bocelli-Tyndall C, Passweg J, Saris D, Tyndall A. The survey on cellular and engineered tissue therapies in Europe in 2010. Tissue Eng Part A. 2012 Nov; 18 (21-22):2268-79 Epub 2012 July 19
    View PubMed
  98. Longo UG, Saris D, Poolman RW, Berton A, Denaro V. Instruments to assess patients with rotator cuff pathology: a systematic review of measurement properties. Knee Surg Sports Traumatol Arthrosc. 2012 Oct; 20 (10):1961-70 Epub 2011 Dec 20
    View PubMed
  99. Malda J, Benders KE, Klein TJ, de Grauw JC, Kik MJ, Hutmacher DW, Saris DB, van Weeren PR, Dhert WJ. Comparative study of depth-dependent characteristics of equine and human osteochondral tissue from the medial and lateral femoral condyles. Osteoarthritis Cartilage. 2012 Oct; 20 (10):1147-51 Epub 2012 July 07
    View PubMed
  100. Rutgers M, Bartels LW, Tsuchida AI, Castelein RM, Dhert WJ, Vincken KL, van Heerwaarden RJ, Saris DB. dGEMRIC as a tool for measuring changes in cartilage quality following high tibial osteotomy: a feasibility study. Osteoarthritis Cartilage. 2012 Oct; 20 (10):1134-41 Epub 2012 July 10
    View PubMed
  101. Meuffels DE, Poldervaart MT, Diercks RL, Fievez AW, Patt TW, Hart CP, Hammacher ER, Meer Fv, Goedhart EA, Lenssen AF, Muller-Ploeger SB, Pols MA, Saris DB. Guideline on anterior cruciate ligament injury. Acta Orthop. 2012 Aug; 83 (4):379-86 Epub 2012 Aug 20
    View PubMed
  102. Vanlauwe J, Huylebroek J, Van Der Bauwhede J, Saris D, Veeckman G, Bobic V, Victor J, Almqvist KF, Verdonk P, Fortems Y, Van Lommel N, Haazen L. Clinical Outcomes of Characterized Chondrocyte Implantation. Cartilage. 2012 Apr; 3 (2):173-80
    View PubMed
  103. Kroon DJ, Kowalski P, Tekieli W, Reeuwijk E, Saris DBF, Slump CH. MRI based knee cartilage assessment. Proceedings Medical Imaging 2012: Computer-Aided Diagnosis (Event: SPIE Medical Imaging, 2012, San Diego, California, United States). 2012; 8315.
  104. Mithoefer K, Peterson L, Saris DB, Mandelbaum BR. Evolution and Current Role of Autologous Chondrocyte Implantation for Treatment of Articular Cartilage Defects in the Football (Soccer) Player. Cartilage. 2012 Jan; 3 (1 Suppl):31S-6S
    View PubMed
  105. Mithoefer K, Peterson L, Saris D, Mandelbaum B, Dvorak J. Special Issue on Articular Cartilage Injury in the Football (Soccer) Player. Cartilage. 2012 Jan; 3 (1 Suppl):4S-5S
    View PubMed
  106. Mandelbaum B, Mithoefer K, Peterson L, Saris D, Dvorak J. Cartilage Issues in Football (Soccer): An Executive Summary of the Federation Internationale de Football Association (FIFA)/ International Cartilage Repair Society (ICRS) Initiative. Cartilage. 2012 Jan; 3 (1 Suppl):6S-10S
    View PubMed
  107. Vanlauwe J, Saris DB, Victor J, Almqvist KF, Bellemans J, Luyten FP, TIG/ACT/01/2000&EXT Study Group. Five-year outcome of characterized chondrocyte implantation versus microfracture for symptomatic cartilage defects of the knee: early treatment matters. Am J Sports Med. 2011 Dec; 39 (12):2566-74 Epub 2011 Sept 09
    View PubMed
  108. Beekhuizen M, Bastiaansen-Jenniskens YM, Koevoet W, Saris DB, Dhert WJ, Creemers LB, van Osch GJ. Osteoarthritic synovial tissue inhibition of proteoglycan production in human osteoarthritic knee cartilage: establishment and characterization of a long-term cartilage-synovium coculture. Arthritis Rheum. 2011 Jul; 63 (7):1918-27
    View PubMed
  109. Mithoefer K, Saris DB, Farr J, Kon E, Zaslav K, Cole BJ, Ranstam J, Yao J, Shive M, Levine D, Dalemans W, Brittberg M. Guidelines for the Design and Conduct of Clinical Studies in Knee Articular Cartilage Repair: International Cartilage Repair Society Recommendations Based on Current Scientific Evidence and Standards of Clinical Care. Cartilage. 2011 Apr; 2 (2):100-21
    View PubMed
  110. Hoemann C, Kandel R, Roberts S, Saris DB, Creemers L, Mainil-Varlet P, Methot S, Hollander AP, Buschmann MD. International Cartilage Repair Society (ICRS) Recommended Guidelines for Histological Endpoints for Cartilage Repair Studies in Animal Models and Clinical Trials. Cartilage. 2011 Apr; 2 (2):153-72
    View PubMed
  111. Assche DV, Caspel DV, Staes F, Saris DB, Bellemans J, Vanlauwe J, Luyten FP. Implementing one standardized rehabilitation protocol following autologous chondrocyte implantation or microfracture in the knee results in comparable physical therapy management. Physiother Theory Pract. 2011 Feb; 27 (2):125-36 Epub 2010 Aug 08
    View PubMed
  112. Benders KE, Malda J, Saris DB, Dhert WJ, Steck R, Hutmacher DW, Klein TJ. Formalin fixation affects equilibrium partitioning of an ionic contrast agent-microcomputed tomography (EPIC-muCT) imaging of osteochondral samples. Osteoarthritis Cartilage. 2010 Dec; 18 (12):1586-91 Epub 2010 Oct 13
    View PubMed
  113. Dijkstra AJ, Anbeek P, Yang KG, Vincken KL, Viergever MA, Castelein RM, Saris DB. Validation of a Novel Semiautomated Segmentation Method for MRI Detection of Cartilage-Related Bone Marrow Lesions. Cartilage. 2010 Oct; 1 (4):328-34
    View PubMed
  114. Bekkers JE, Creemers LB, Dhert WJ, Saris DB. Diagnostic Modalities for Diseased Articular Cartilage-From Defect to Degeneration: A Review. Cartilage. 2010 Jul; 1 (3):157-64
    View PubMed
  115. Van Assche D, Staes F, Van Caspel D, Vanlauwe J, Bellemans J, Saris DB, Luyten FP. Autologous chondrocyte implantation versus microfracture for knee cartilage injury: a prospective randomized trial, with 2-year follow-up. Knee Surg Sports Traumatol Arthrosc. 2010 Apr; 18 (4):486-95 Epub 2009 Oct 10
    View PubMed
  116. Custers RJ, Saris DB, Creemers LB, Verbout AJ, van Rijen MH, Mastbergen SC, Lafeber FP, Dhert WJ. Replacement of the medial tibial plateau by a metallic implant in a goat model. J Orthop Res. 2010 Apr; 28 (4):429-35
    View PubMed
  117. Custers RJ, Dhert WJ, Saris DB, Verbout AJ, van Rijen MH, Mastbergen SC, Lafeber FP, Creemers LB. Cartilage degeneration in the goat knee caused by treating localized cartilage defects with metal implants. Osteoarthritis Cartilage. 2010 Mar; 18 (3):377-88 Epub 2009 Oct 23
    View PubMed
  118. Bekkers JE, Tsuchida AI, Malda J, Creemers LB, Castelein RJ, Saris DB, Dhert WJ. Quality of scaffold fixation in a human cadaver knee model. Osteoarthritis Cartilage. 2010 Feb; 18 (2):266-72 Epub 2009 Sept 22
    View PubMed
  119. Rutgers M, van Pelt MJ, Dhert WJ, Creemers LB, Saris DB. Evaluation of histological scoring systems for tissue-engineered, repaired and osteoarthritic cartilage. Osteoarthritis Cartilage. 2010 Jan; 18 (1):12-23 Epub 2009 Sept 02
    View PubMed
  120. Buckens CF, Saris DB. Reconstruction of the medial patellofemoral ligament for treatment of patellofemoral instability: a systematic review. Am J Sports Med. 2010 Jan; 38 (1):181-8 Epub 2009 Dec 04
    View PubMed
  121. Rutgers M, Saris DB, Dhert WJ, Creemers LB. Cytokine profile of autologous conditioned serum for treatment of osteoarthritis, in vitro effects on cartilage metabolism and intra-articular levels after injection. Arthritis Res Ther. 2010; 12 (3):R114 Epub 2010 June 10
    View PubMed
  122. Bekkers JE, de Windt TS, Raijmakers NJ, Dhert WJ, Saris DB. Validation of the Knee Injury and Osteoarthritis Outcome Score (KOOS) for the treatment of focal cartilage lesions. Osteoarthritis Cartilage. 2009 Nov; 17 (11):1434-9 Epub 2009 May 07
    View PubMed
  123. Saris DB, Vanlauwe J, Victor J, Almqvist KF, Verdonk R, Bellemans J, Luyten FP, TIG/ACT/01/2000&EXT Study Group. Treatment of symptomatic cartilage defects of the knee: characterized chondrocyte implantation results in better clinical outcome at 36 months in a randomized trial compared to microfracture. Am J Sports Med. 2009 Nov; 37 Suppl 1:10S-19S Epub 2009 Oct 21
    View PubMed
  124. Van Assche D, Van Caspel D, Vanlauwe J, Bellemans J, Saris DB, Luyten FP, Staes F. Physical activity levels after characterized chondrocyte implantation versus microfracture in the knee and the relationship to objective functional outcome with 2-year follow-up. Am J Sports Med. 2009 Nov; 37 Suppl 1:42S-49S Epub 2009 Oct 27
    View PubMed
  125. de Windt TS, Bekkers JE, Creemers LB, Dhert WJ, Saris DB. Patient profiling in cartilage regeneration: prognostic factors determining success of treatment for cartilage defects. Am J Sports Med. 2009 Nov; 37 Suppl 1:58S-62S
    View PubMed
  126. Bekkers JE, Inklaar M, Saris DB. Treatment selection in articular cartilage lesions of the knee: a systematic review. Am J Sports Med. 2009 Nov; 37 Suppl 1:148S-55S
    View PubMed
  127. van Eijk F, Saris DB, Fedorovich NE, Kruyt MC, Willems WJ, Verbout AJ, Martens AC, Dhert WJ, Creemers L. In vivo matrix production by bone marrow stromal cells seeded on PLGA scaffolds for ligament tissue engineering. Tissue Eng Part A. 2009 Oct; 15 (10):3109-17
    View PubMed
  128. Rutgers M, Saris DB, Yang KG, Dhert WJ, Creemers LB. Joint injury and osteoarthritis: soluble mediators in the course and treatment of cartilage pathology. Immunotherapy. 2009 May; 1 (3):435-45
    View PubMed
  129. de Boer TN, Huisman AM, Polak AA, Niehoff AG, van Rinsum AC, Saris D, Bijlsma JW, Lafeber FJ, Mastbergen SC. The chondroprotective effect of selective COX-2 inhibition in osteoarthritis: ex vivo evaluation of human cartilage tissue after in vivo treatment. Osteoarthritis Cartilage. 2009 Apr; 17 (4):482-8 Epub 2008 Oct 15
    View PubMed
  130. Custers RJ, Saris DB, Dhert WJ, Verbout AJ, van Rijen MH, Mastbergen SC, Lafeber FP, Creemers LB. Articular cartilage degeneration following the treatment of focal cartilage defects with ceramic metal implants and compared with microfracture. J Bone Joint Surg Am. 2009 Apr; 91 (4):900-10
    View PubMed
  131. Custers RJ, Creemers LB, van Rijen MH, Verbout AJ, Saris DB, Dhert WJ. Cartilage damage caused by metal implants applied for the treatment of established localized cartilage defects in a rabbit model. J Orthop Res. 2009 Jan; 27 (1):84-90
    View PubMed
  132. van Eijk F, Saris DB, Creemers LB, Riesle J, Willems WJ, van Blitterswijk CA, Verbout AJ, Dhert WJ. The effect of timing of mechanical stimulation on proliferation and differentiation of goat bone marrow stem cells cultured on braided PLGA scaffolds. Tissue Eng Part A. 2008 Aug; 14 (8):1425-33
    View PubMed
  133. Auw Yang KG, Raijmakers NJ, van Arkel ER, Caron JJ, Rijk PC, Willems WJ, Zijl JA, Verbout AJ, Dhert WJ, Saris DB. Autologous interleukin-1 receptor antagonist improves function and symptoms in osteoarthritis when compared to placebo in a prospective randomized controlled trial. Osteoarthritis Cartilage. 2008 Apr; 16 (4):498-505 Epub 2007 Sept 06
    View PubMed
  134. Marijnissen AC, Vincken KL, Vos PA, Saris DB, Viergever MA, Bijlsma JW, Bartels LW, Lafeber FP. Knee Images Digital Analysis (KIDA): a novel method to quantify individual radiographic features of knee osteoarthritis in detail. Osteoarthritis Cartilage. 2008 Feb; 16 (2):234-43 Epub 2007 Aug 10
    View PubMed
  135. Saris DB, Vanlauwe J, Victor J, Haspl M, Bohnsack M, Fortems Y, Vandekerckhove B, Almqvist KF, Claes T, Handelberg F, Lagae K, van der Bauwhede J, Vandenneucker H, Yang KG, Jelic M, Verdonk R, Veulemans N, Bellemans J, Luyten FP. Characterized chondrocyte implantation results in better structural repair when treating symptomatic cartilage defects of the knee in a randomized controlled trial versus microfracture. Am J Sports Med. 2008 Feb; 36 (2):235-46
    View PubMed
  136. van Dijck RA, Saris DB, Willems JW, Fievez AW. Additional surgery after anterior cruciate ligament reconstruction: can we improve technical aspects of the initial procedure? Arthroscopy. 2008 Jan; 24 (1):88-95 Epub 2007 Nov 05
    View PubMed
  137. van den Borne MP, Raijmakers NJ, Vanlauwe J, Victor J, de Jong SN, Bellemans J, Saris DB, International Cartilage Repair Society. International Cartilage Repair Society (ICRS) and Oswestry macroscopic cartilage evaluation scores validated for use in Autologous Chondrocyte Implantation (ACI) and microfracture. Osteoarthritis Cartilage. 2007 Dec; 15 (12):1397-402 Epub 2007 July 02
    View PubMed
  138. Custers RJ, Creemers LB, Verbout AJ, van Rijen MH, Dhert WJ, Saris DB. Reliability, reproducibility and variability of the traditional Histologic/Histochemical Grading System vs the new OARSI Osteoarthritis Cartilage Histopathology Assessment System. Osteoarthritis Cartilage. 2007 Nov; 15 (11):1241-8 Epub 2007 June 18
    View PubMed
  139. Custers RJ, Dhert WJ, van Rijen MH, Verbout AJ, Creemers LB, Saris DB. Articular damage caused by metal plugs in a rabbit model for treatment of localized cartilage defects. Osteoarthritis Cartilage. 2007 Aug; 15 (8):937-45 Epub 2007 Mar 21
    View PubMed
  140. Jenner JM, van Eijk F, Saris DB, Willems WJ, Dhert WJ, Creemers LB. Effect of transforming growth factor-beta and growth differentiation factor-5 on proliferation and matrix production by human bone marrow stromal cells cultured on braided poly lactic-co-glycolic acid scaffolds for ligament tissue engineering. Tissue Eng. 2007 Jul; 13 (7):1573-82
    View PubMed
  141. de Jong SN, van Caspel DR, van Haeff MJ, Saris DB. Functional assessment and muscle strength before and after reconstruction of chronic anterior cruciate ligament lesions. Arthroscopy. 2007 Jan; 23 (1):21-8, 28.e1-3
    View PubMed
  142. Yang KG, Raijmakers NJ, Verbout AJ, Dhert WJ, Saris DB. Validation of the short-form WOMAC function scale for the evaluation of osteoarthritis of the knee. J Bone Joint Surg Br. 2007 Jan; 89 (1):50-6
    View PubMed
  143. van Oostveen DP, Schild FJ, van Haeff MJ, Saris DB. Suture anchors are superior to transglenoid sutures in arthroscopic shoulder stabilization. Arthroscopy. 2006 Dec; 22 (12):1290-7
    View PubMed
  144. Yang KG, Saris DB, Verbout AJ, Creemers LB, Dhert WJ. The effect of synovial fluid from injured knee joints on in vitro chondrogenesis. Tissue Eng. 2006 Oct; 12 (10):2957-64
    View PubMed
  145. Yang KG, Saris DB, Geuze RE, Helm YJ, Rijen MH, Verbout AJ, Dhert WJ, Creemers LB. Impact of expansion and redifferentiation conditions on chondrogenic capacity of cultured chondrocytes. Tissue Eng. 2006 Sep; 12 (9):2435-47
    View PubMed
  146. Yang KG, Saris DB, Geuze RE, van Rijen MH, van der Helm YJ, Verbout AJ, Creemers LB, Dhert WJ. Altered in vitro chondrogenic properties of chondrocytes harvested from unaffected cartilage in osteoarthritic joints. Osteoarthritis Cartilage. 2006 Jun; 14 (6):561-70
    View PubMed
  147. Schep NW, Stavenuiter MH, Diekerhof CH, Martens EP, van Haeff CM, Broeders IA, Saris DB. Intersurgeon variance in computer-assisted planning of anterior cruciate ligament reconstruction. Arthroscopy. 2005 Aug; 21 (8):942-7
    View PubMed
  148. Van Eijk F, Saris DB, Riesle J, Willems WJ, Van Blitterswijk CA, Verbout AJ, Dhert WJ. Tissue engineering of ligaments: a comparison of bone marrow stromal cells, anterior cruciate ligament, and skin fibroblasts as cell source. Tissue Eng. 2004 May-Jun; 10 (5-6):893-903
    View PubMed
  149. Reinholz GG, Lu L, Saris DB, Yaszemski MJ, O'Driscoll SW. Animal models for cartilage reconstruction. Biomaterials. 2004 Apr; 25 (9):1511-21
    View PubMed
  150. Auw Yang KG, Saris, Dhert, Verbout AJ. Osteoarthritis of the Knee: Current treatment options and future directions. Current Orthopaedics. 2004; 18:311-320.
  151. Saris DB, Dhert WJ, Verbout AJ. Joint homeostasis. The discrepancy between old and fresh defects in cartilage repair. J Bone Joint Surg Br. 2003 Sep; 85 (7):1067-76
    View PubMed
  152. Moojen DJ, Saris DB, Auw Yang KG, Dhert WJ, Verbout AJ. The correlation and reproducibility of histological scoring systems in cartilage repair. Tissue Eng. 2002 Aug; 8 (4):627-34
    View PubMed
  153. Mukherjee N, Saris DB, Schultz FM, Berglund LJ, An KN, O' Driscoll SW. The enhancement of periosteal chondrogenesis in organ culture by dynamic fluid pressure. J Orthop Res. 2001 Jul; 19 (4):524-30
    View PubMed
  154. O'Driscoll SW, Saris DB, Ito Y, Fitzimmons JS. The chondrogenic potential of periosteum decreases with age. J Orthop Res. 2001 Jan; 19 (1):95-103
    View PubMed
  155. Saris DB, Mukherjee N, Berglund LJ, Schultz FM, An KN, O'Driscoll SW. Dynamic pressure transmission through agarose gels. Tissue Eng. 2000 Oct; 6(5):531-7.
    View PubMed
  156. Sanyal A, Sarkar G, Saris DB, Fitzsimmons JS, Bolander ME, O'Driscoll SW. Initial evidence for the involvement of bone morphogenetic protein-2 early during periosteal chondrogenesis. J Orthop Res. 1999 Nov; 17(6):926-34.
    View PubMed
  157. Saris DB, Sanyal A, An KN, Fitzsimmons JS, O'Driscoll SW. Periosteum responds to dynamic fluid pressure by proliferating in vitro. J Orthop Res. 1999 Sep; 17(5):668-77.
    View PubMed
  158. Schroder J, Saris D, Besselaar PP, Marti RK. Comparison of the results of the Girdlestone pseudarthrosis with reimplantation of a total hip replacement. Int Orthop. 1998; 22 (4):215-8
    View PubMed
  159. Saris DB, van Rinsum AC, Dhert WJ, Roosendaal G, Mali WP. Periarticular aneurysm formation in haemophilia. Lancet. 1997 Mar 15; 349 (9054):766-8
    View PubMed
PST-20421024