Francis (Frank) X. Downey, III, M.D.

  1. Cardiovascular Surgeon

Publications

  1. Sen A, Blakeman S, DeValeria PA, Peworski D, Lanza LA, Downey FX, Alwardt CM, Dobberpuhl JG, DeMarco M, Callisen H, Shively J, McKay K, Singbartl K, Sell-Dottin KA, D'Cunha J, Patel BM. Practical Considerations for and Outcomes of Interfacility ECMO Transfer of Patients With COVID-19 During a Pandemic: Mayo Clinic Experience. Mayo Clin Proc Innov Qual Outcomes. 2021 Apr; 5 (2):525-531 Epub 2021 Mar 03
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  2. Thohan V, Michel K, Purohit A, Malick O, Downey FX, Oaks M. The effect of pre-transplant and post-transplant anti-AT1R antibodies in heart transplant recipients. Transplant Rep. 2020; 5(4):Article 100069.
  3. Emelyanova L, Sra A, Schmuck EG, Raval AN, Downey FX, Jahangir A, Rizvi F, Ross GR. Impact of statins on cellular respiration and de-differentiation of myofibroblasts in human failing hearts. ESC Heart Fail. 2019 Oct; 6 (5):1027-1040 Epub 2019 Sept 14
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  4. Ross GR, Edwards S, Warner C, Homar P, Downey FX, Emelyanova L, Rizvi F, Jahangir A. Deletion of transcription factor AP-2alpha gene attenuates fibroblast differentiation into myofibroblast. J Cell Mol Med. 2019 Sep; 23 (9):6494-6498 Epub 2019 July 24
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  5. Colombo PC, Mehra MR, Goldstein DJ, Estep JD, Salerno C, Jorde UP, Cowger JA, Cleveland JC Jr, Uriel N, Sayer G, Skipper ER, Downey FX, Ono M, Hooker R Jr, Anyanwu AC, Givertz MM, Mahr C, Topuria I, Somo SI, Crandall DL, Horstmanshof DA. Comprehensive Analysis of Stroke in the Long-Term Cohort of the MOMENTUM 3 Study. Circulation. 2019 Jan 8; 139 (2):155-168
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  6. Oaks M, Michel K, Downey FX, Thohan V. Xenoreactive antibodies and latent fibrin formation in VAD and cardiac transplant recipients can confound the detection and measurement of anti-AT1R antibodies. Am J Transplant. 2018 Nov; 18 (11):2763-2771 Epub 2018 Apr 24
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  7. Ross GR, Bajwa T Jr, Edwards S, Emelyanova L, Rizvi F, Holmuhamedov EL, Werner P, Downey FX, Tajik AJ, Jahangir A. Enhanced store-operated Ca(2+) influx and ORAI1 expression in ventricular fibroblasts from human failing heart. Biol Open. 2017 Mar 15; 6 (3):326-332
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  8. Thohan V, Murtaza G, Encarnacion CO, Sulemanjee N, Cheema O, Hastings T, Cho C, Downey F, Crouch J. Favorable outcomes of LVAD as bridge to simultaneous heart-kidney transplantation. The VAD Journal. 2016 Dec 4; 2(1):27.
  9. Longobardo L, Kramer C, Carerj S, Zito C, Jain R, Suma V, Thohan V, Sulemanjee N, Downey FX, Khandheria BK. Role of Echocardiography in the Evaluation of Left Ventricular Assist Devices: the Importance of Emerging Technologies. Curr Cardiol Rep. 2016 Jul; 18 (7):62
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  10. Michel K, Santella R, Steers J, Sahajpal A, Downey FX, Thohan V, Oaks M. Many de novo donor-specific antibodies recognize beta2 -microglobulin-free, but not intact HLA heterodimers. HLA. 2016 May; 87 (5):356-66 Epub 2016 Apr 06
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  11. Turagam MK, Downey FX, Kress DC, Sra J, Tajik AJ, Jahangir A. Pharmacological strategies for prevention of postoperative atrial fibrillation. Expert Rev Clin Pharmacol. 2015 Mar; 8 (2):233-50
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  12. Oaks M, Michel K, Sulemanjee NZ, Thohan V, Downey FX. Practical value of identifying antibodies to cryptic HLA epitopes in cardiac transplantation. J Heart Lung Transplant. 2014 Jul; 33 (7):713-20 Epub 2014 Feb 14
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  13. Agarwal A, Sulemanjee NZ, Cheema O, Downey FX, Tajik AJ. Cardiac sarcoid: a chameleon masquerading as hypertrophic cardiomyopathy and dilated cardiomyopathy in the same patient. Echocardiography. 2014 May; 31 (5):E138-41 Epub 2014 Feb 08
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  14. Kress DC, Aronson S, McDonald ML, Malik MI, Divgi AB, Tector AJ, Downey FX 3rd, Anderson AJ, Stone M, Clancy C. Positive heparin-platelet factor 4 antibody complex and cardiac surgical outcomes. Ann Thorac Surg. 2007 May; 83 (5):1737-43
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  15. Kalya AV, Tector AJ, Crouch JD, Downey FX, McDonald ML, Anderson AJ, Bartoszewski CJ, Hosenpud JD. Comparison of Novacor and HeartMate vented electric left ventricular assist devices in a single institution. J Heart Lung Transplant. 2005 Nov; 24(11):1973-5.
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  16. Kress DC, Trector AJ, Downey FX, McDonald MM. Off pump microwave ablation of atrial fibrillation during mitral valve surgery. Operative Techniques in Cardiovascular & Thoracic Surgery. 2004 Spring; 9(1):43-58.
  17. Ortolano GA, Aldea GS, Lilly K, O'Gara P, Alkon JD, Mader F, Murad T, Altenbern CP, Tritt CS, Capetandes A, Gikakis NS, Wenz B, Shemin RJ, Downey FX 3rd. A review of leukofiltration in cardiac surgery: the time course of reperfusion injury may facilitate study design of anti-inflammatory effects. Perfusion. 2002 May; 17 Suppl:53-62
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  18. Tector AJ, McDonald ML, Kress DC, Downey FX, Schmahl TM. Purely internal thoracic artery grafts: outcomes. Ann Thorac Surg. 2001 Aug; 72 (2):450-5
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  19. Ortolano GA, Gikakis NS, Aldea GS, Lilly K, O'Gara P, Alkon JD, Madera F, Murad T, Altenbern C, Tritt C, Downey FX. Risk neutralization in cardiac surgery with leukocyte reducing filters. Proc Am Acad Cardiovasc Perfusion. 1999; 20:97-101.
  20. Webb DP, Altenbern CP, Tritt C, Downey FX, Minkel D. Pulmonary implications of filtering various mediators of morbidity found in salvaged blood. The Journal of Extra-Corporeal Technology. 1998 Sep; 30(3):108-14.
  21. Tector AJ, Kress DC, Downey FX, Schmahl TM, Dasse KA, Poirier VL. Transition from cardiopulmonary bypass to the HeartMate left ventricular assist device. Ann Thorac Surg. 1998 Mar; 65 (3):643-6
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  22. Tector AJ, Kress DC, Downey FX, Schmahl TM. Use of internal thoracic artery T-grafts for complete arterial revascularization. Operative Techniques in Cardiac & Thoracic Surgery. 1996 Oct; 1(2):108-16.
  23. Tector AJ, Kress DC, Downey FX, Schmahl TM. Complete revascularization with internal thoracic artery grafts. Semin Thorac Cardiovasc Surg. 1996 Jan; 8 (1):29-41
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  24. Freeman J, DeLeon SY, Miles RH, Downey FX, Hofstra J, Quinones JA, Fisher EA, Pifarre R. Acute pulmonary hypertension complicating the arterial switch procedure. Pediatr Cardiol. 1995 Nov-Dec; 16 (6):297-300
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  25. Tector AJ, Kress DC, Amundsen SM, Downey FX, Schmahl TM. Reoperation in patients with closed SVG and patient LITA-LAD graft: T-graft approach. Ann Thorac Surg. 1995 Jun; 59 (6):1509-12
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  26. Downey FX, DeLeon SY, Monson DO, Baumgartner NE, Lichtenberg RC, Sullivan HJ, Pifarre R. Disruption of sutured pulmonary valve in Fontan operation. Ann Thorac Surg. 1994 Nov; 58 (5):1527-9
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  27. DeLeon SY, Downey FX, Baumgartner NE, Ow EP, Quinones JA, Torres L, Ilbawi MN, Pifarre R. Transsternal repair of coarctation and associated cardiac defects. Ann Thorac Surg. 1994 Jul; 58 (1):179-83; discussion 183-4
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  28. DeLeon SY, Freeman JE, Ow EP, Quinones JA, Bell TJ, Fisher EA, Downey FX, Sullivan HJ, Pifarre R. Obligatory Glenn shunt in fenestrated Fontan. Ann Thorac Surg. 1993 Sep; 56 (3):510-4
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PST-20478029