الأدوية والمكملات الغذائية

Before Using

Drug information provided by: Merative, Micromedex®

If you are taking a dietary supplement without a prescription, carefully read and follow any precautions on the label. For these supplements, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Problems in children have not been reported with intake of normal daily recommended amounts. However, use of enemas that contain phosphates in children has resulted in high blood levels of phosphorus.

Geriatric

Problems in older adults have not been reported with intake of normal daily recommended amounts.

Pregnancy

It is especially important that you are receiving enough vitamins and minerals when you become pregnant and that you continue to receive the right amount of vitamins and minerals throughout your pregnancy. The healthy growth and development of the fetus depend on a steady supply of nutrients from the mother. However, taking large amounts of a dietary supplement in pregnancy may be harmful to the mother and/or fetus and should be avoided.

Breastfeeding

It is especially important that you receive the right amount of vitamins and minerals so that your baby will also get the vitamins and minerals needed to grow properly. However, taking large amounts of a dietary supplement while breast-feeding may be harmful to the mother and/or baby and should be avoided.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking any of these dietary supplements, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using dietary supplements in this class with any of the following medicines is not recommended. Your doctor may decide not to treat you with dietary supplements in this class or change some of the other medicines you take.

• Bepridil
• Burosumab-twza
• Calcifediol
• Calcitriol
• Cisapride
• Dihydrotachysterol
• Doxercalciferol
• Dronedarone
• Eplerenone
• Fesoterodine
• Glycopyrrolate
• Levoketoconazole
• Mesoridazine
• Paricalcitol
• Pimozide
• Piperaquine
• Potassium Phosphate
• Saquinavir
• Sodium Phosphate, Dibasic
• Sodium Phosphate, Monobasic
• Sparfloxacin
• Terfenadine
• Thioridazine
• Trospium
• Ziprasidone

Using dietary supplements in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Adagrasib
• Alacepril
• Alfuzosin
• Amiloride
• Amiodarone
• Amisulpride
• Amitriptyline
• Amoxapine
• Anagrelide
• Apomorphine
• Aripiprazole
• Aripiprazole Lauroxil
• Arsenic Trioxide
• Asenapine
• Astemizole
• Atazanavir
• Azilsartan
• Azilsartan Medoxomil
• Azithromycin
• Bedaquiline
• Benazepril
• Buprenorphine
• Buserelin
• Candesartan
• Canrenoate
• Canrenone
• Captopril
• Ceritinib
• Chloroquine
• Chlorpromazine
• Cilazapril
• Ciprofloxacin
• Citalopram
• Clarithromycin
• Clofazimine
• Clomipramine
• Clothiapine
• Clozapine
• Crizotinib
• Cyclobenzaprine
• Cyclosporine
• Dabrafenib
• Dasatinib
• Degarelix
• Delamanid
• Delapril
• Desipramine
• Deslorelin
• Deutetrabenazine
• Dexmedetomidine
• Digoxin
• Disopyramide
• Dofetilide
• Dolasetron
• Domperidone
• Donepezil
• Droperidol
• Efavirenz
• Enalapril
• Enalaprilat
• Encorafenib
• Entrectinib
• Eplerenone
• Eprosartan
• Erdafitinib
• Erythromycin
• Escitalopram
• Etrasimod
• Fexinidazole
• Fingolimod
• Flecainide
• Fluconazole
• Fluoxetine
• Formoterol
• Foscarnet
• Fosinopril
• Fostemsavir
• Gatifloxacin
• Gemifloxacin
• Gepirone
• Glasdegib
• Gonadorelin
• Goserelin
• Granisetron
• Halofantrine
• Haloperidol
• Histrelin
• Hydroxychloroquine
• Hydroxyzine
• Ibutilide
• Iloperidone
• Imidapril
• Imipramine
• Indomethacin
• Inotuzumab Ozogamicin
• Irbesartan
• Ivabradine
• Ivosidenib
• Ketoconazole
• Lapatinib
• Lefamulin
• Lenvatinib
• Leuprolide
• Levofloxacin
• Lisinopril
• Lofexidine
• Lopinavir
• Losartan
• Lumefantrine
• Macimorelin
• Mefloquine
• Methadone
• Metronidazole
• Mifepristone
• Mirtazapine
• Mobocertinib
• Moexipril
• Moxifloxacin
• Nafarelin
• Nilotinib
• Norfloxacin
• Nortriptyline
• Octreotide
• Ofloxacin
• Olanzapine
• Olmesartan
• Ondansetron
• Osilodrostat
• Osimertinib
• Oxaliplatin
• Ozanimod
• Pacritinib
• Paliperidone
• Panobinostat
• Paroxetine
• Pasireotide
• Pazopanib
• Pentopril
• Perindopril
• Phenobarbital
• Pimavanserin
• Pitolisant
• Ponesimod
• Posaconazole
• Primidone
• Procainamide
• Prochlorperazine
• Promethazine
• Propafenone
• Protriptyline
• Quetiapine
• Quinapril
• Quinidine
• Quinine
• Quizartinib
• Ramipril
• Ranolazine
• Relugolix
• Ribociclib
• Selpercatinib
• Sertraline
• Sevoflurane
• Siponimod
• Solifenacin
• Sorafenib
• Sotalol
• Sparsentan
• Spirapril
• Spironolactone
• Sulpiride
• Sunitinib
• Tacrolimus
• Telavancin
• Telithromycin
• Telmisartan
• Temocapril
• Tetrabenazine
• Toremifene
• Trandolapril
• Trazodone
• Triamterene
• Triclabendazole
• Trifluoperazine
• Trimipramine
• Triptorelin
• Valsartan
• Vandetanib
• Vardenafil
• Vemurafenib
• Venlafaxine
• Vilanterol
• Vinflunine
• Voclosporin
• Voriconazole
• Zofenopril
• Zuclopenthixol

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of dietary supplements in this class. Make sure you tell your doctor if you have any other medical problems, especially:

• Burns, severe or
• Heart disease or
• Pancreatitis (inflammation of the pancreas) or
• Rickets or
• Softening of bones or
• Underactive parathyroid glands—Sodium- or potassium-containing phosphates may make these conditions worse.

• Dehydration or
• Underactive adrenal glands—Potassium-containing phosphates may increase the risk of hyperkalemia (too much potassium in the blood).

• Edema (swelling in feet or lower legs or fluid in lungs) or
• High blood pressure or
• Liver disease or
• Toxemia of pregnancy—Sodium-containing phosphates may make these conditions worse.

• High blood levels of phosphate (hyperphosphatemia)—Use of phosphates may make this condition worse.

• Infected kidney stones—Phosphates may make this condition worse.

• Kidney disease—Sodium-containing phosphates may make this condition worse; potassium-containing phosphates may increase the risk of hyperkalemia (too much potassium in the blood).

• Myotonia congenita—Potassium-containing phosphates may increase the risk of hyperkalemia (too much potassium in the blood), and make this condition worse.