Drug information provided by: Merative, Micromedex®

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood and urine tests may be needed to check for unwanted effects.

This medicine may cause kidney problems. Tell your doctor right away if you have decreased urine output, depression, dizziness, a headache, lethargy, muscle twitching, nausea, rapid weight gain, seizures, swelling of the face, ankles, or hands, or unusual tiredness or weakness after taking this medicine.

Heart or blood vessel problems may occur with this medicine. Tell your doctor if you have chest pain or discomfort, confusion, nausea or vomiting, pain or discomfort in the arms, jaw, back, or neck, sweating, trouble speaking, or slow speech, or are unable to move your arms, legs, or facial muscles.

Birth control pills, patches, and injections may not work as well while you are using lesinurad. Use another form of birth control together with your birth control pills to keep from getting pregnant. Check with your doctor if you have any questions.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.