Proper Use

Drug information provided by: Merative, Micromedex®

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine comes with a patient information leaflet and patient instructions. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Take this medicine in the morning on an empty stomach. Do not eat or drink anything at bedtime for at least 8 hours if you eat a high-fat meal, 4 hours if a low-fat meal, or 2 hours if you take a calorie supplement.

Do not eat or drink anything except water for 1 hour after taking this medicine.

To use:

  • This medicine can be taken by the mouth or be given through nasogastric or PEG tubes.
  • Shake the bottle well for at least 30 seconds until no small pieces at the bottom before each use.
  • Measure the oral liquid medicine with the provided oral dosing syringe. The average household teaspoon may not hold the right amount of liquid.
  • Place the tip of the oral syringe in the mouth towards inside of the cheek. Swallow all the medicine. You may also use 8 ounces or 1 cup of water to help you swallow the medicine.
  • If it is given through a feeding tube: Using a catheter-tip syringe, rinse the feeding tube with 30 milliliters (mL) of water. Then, inject the oral syringe with medicine into the feeding tube and rinse the tube with 30 mL water.

If you are receiving the injection form of this medicine, your doctor may switch you to the oral liquid form. Ask your doctor if you have questions.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage forms (suspension):
    • For amyotrophic lateral sclerosis (ALS):
      • Adults—
        • First treatment cycle—105 milligrams (mg) or 5 milliliters (mL) once a day in the morning for 14 days, followed by 14 days without the medicine.
        • For cycles after the first treatment cycle—105 mg or 5 mL once a day in the morning for 10 days, followed by 14 days without the medicine.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Keep the bottle closed when you are not using it. Store it at room temperature, away from light and heat. Do not freeze.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Throw away any unused liquid after 15 days of opening the bottle or 30 days from the date of shipment on the carton label, whichever comes first.