Precautions

Drug information provided by: Merative, Micromedex®

It is very important that your doctor check you or your child's progress at regular visits to make sure that this medicine is working properly. Blood and urine tests may be needed to check for unwanted effects.

This medicine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and requires immediate medical attention. Tell your doctor right away if you or your child have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of the hands, face, or mouth after using this medicine.

This medicine may cause redistribution of body fat or thickening, depression, or indentation of the skin at the injection site after several months of using it. Make sure to follow the instructions on the proper way of injecting the medicine and to rotate the injection sites regularly. Use 2 separate injection sites when giving 2 doses of this medicine.

This medicine may cause calcium to build-up in the eyes or kidneys, which could lead to more serious unwanted effects. Check with your doctor right away if you or you child have redness or dryness of the eye, difficult or painful urination, bloody urine, nausea, vomiting, pain in the groin or genitals, sharp back pain just below the ribs, or if you or your child see floating dark spots or material before the eyes.

Asfotase alfa may possibly cause the body to develop antibodies against it, which can lessen the effects of this medicine. If your or your child's symptoms do not improve within a few days, or if they become worse, check with your doctor.

Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.