Chad M. Ruoff, M.D.

  1. Sleep Medicine Specialist
  1. Carvalho DZ, Mansukhani MP, St. EK, Ruoff CM, Kolla BP. Aging and sex are associated with multiple sleep latency test findings and their relationship with self-reported sleepiness Sleep and Biological Rhythms. 2024.
  2. Rosenberg R, Braceras R, Macfadden W, Candler S, Black J, Ruoff C. Implications of Oxybate Dosing Regimen for Sleep, Sleep Architecture, and Disrupted Nighttime Sleep in Patients with Narcolepsy: A Commentary. Neurol Ther. 2023 Dec; 12 (6):1805-1820 Epub 2023 Sept 27
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  3. Castellanos PL, Satashia P, Punj M, Castillo PR, Colaco BM, Dredla BK, Festic E, Kaplan J, Ruoff CM, Speicher LL, Walsh KL, Werninck N, Yin M, Burger CD, Arunthari V, Cheung J. Assessment of sleep quality and sleep disordered breathing among post-hospitalized patients with COVID-19. Front Sleep. 2023; 2:1214036.
  4. Ruoff CM, Tashman YS, Cheema KPK, Miller BW, Houser RF, Lizak MJ, Haley CC, Petersen AM, Goswami U, Lyng PJ, Krahn LE, Srivathsan K. Interaction of positive airway pressure mask magnets with cardiac implantable electronic devices. J Clin Sleep Med. 2023 May 1; 19 (5):941-946
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  5. McCarter SJ, Auger RR, Ruoff CM, St Louis EK. Irregular sleep-wake rhythm disorder Masquerading as hypersomnia in Moebius syndrome. Sleep Med. 2023 Mar; 103:14-15 Epub 2023 Jan 14
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  6. Devarajan A, Paliwal A, Ruoff C, Lyng PJ, Lizak M, Krahn LE. Interaction between alcohol consumption and use of peripheral arterial tone home sleep apnea tests for sleep apnea evaluation. Sleep Med. 2023 Feb; 102:142-146 Epub 2022 Dec 30
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  7. Devarajan A, Roderick MR, Miller BW, Ruoff CM. A Case of Catathrenia Captured on Polysomnography with Audio-Visual Recording. Am J Respir Crit Care Med. 2022 Nov 15; 206 (10):1281-1283
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  8. Lecendreux M, Plazzi G, Dauvilliers Y, Rosen CL, Ruoff C, Black J, Parvataneni R, Guinta D, Wang YG, Mignot E. Long-term safety and maintenance of efficacy of sodium oxybate in the treatment of narcolepsy with cataplexy in pediatric patients. J Clin Sleep Med. 2022 Sep 1; 18 (9):2217-2227
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  9. Krahn LE, Arand DL, Avidan AY, Davila DG, DeBassio WA, Ruoff CM, Harrod CG. Recommended protocols for the Multiple Sleep Latency Test and Maintenance of Wakefulness Test in adults: guidance from the American Academy of Sleep Medicine. J Clin Sleep Med. 2021 Dec 1; 17 (12):2489-2498
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  10. Chen C, Rosen CL, Ruoff C, Boyce LH, Parvataneni R, Zomorodi K, Brantley S, Sale M, Plazzi G. Population and Noncompartmental Pharmacokinetics of Sodium Oxybate Support Weight-Based Dosing in Children and Adolescents With Narcolepsy With Cataplexy. Clin Transl Sci. 2020 Sep; 13 (5):932-940 Epub 2020 Apr 18
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  11. Plazzi G, Ruoff C, Lecendreux M, Dauvilliers Y, Rosen CL, Black J, Parvataneni R, Guinta D, Wang YG, Mignot E. Treatment of paediatric narcolepsy with sodium oxybate: a double-blind, placebo-controlled, randomised-withdrawal multicentre study and open-label investigation. Lancet Child Adolesc Health. 2018 Jul; 2 (7):483-494 Epub 2018 May 21
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  12. Scapuccin M, Schneider L, Rashid N, Zaghi S, Rosa T, Tsou YA, Liu S, Lazarini P, Capasso R, Ruoff C. Integrating the Divided Nasal Cannula Into Routine Polysomnography to Assess Nasal Cycle: Feasibility and Effect on Outcomes. J Clin Sleep Med. 2018 Apr 15; 14 (4):641-650
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  13. Scapuccin M, Schneider L, Rashid N, Zaghi S, Rosa T, David Liu S, Lazarini P, Capasso R, Ruoff C. Feasibility and Utility of Independent Nasal Flow Monitoring During Routine Polysomnograms: The Nasal Cycle. J Clin Sleep Medicine. 2018 Mar.
  14. Cheung J, Ruoff C, Moore H, Hagerman KA, Perez J, Sakamuri S, Warby SC, Mignot E, Day J, Sampson J. Increased EEG Theta Spectral Power in Sleep in Myotonic Dystrophy Type 1. J Clin Sleep Med. 2018 Feb 15; 14 (2):229-235
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  15. Cheung J, Ruoff C, Hagerman K, Day J, Mignot E, Sampson J. Increased Theta Power in Myotonic Dystrophy J Clin Sleep Medicine. 2018 Feb; 14(2):229-35.
  16. Ruoff C, Pizza F, Trotti LM, Sonka K, Vandi S, Cheung J, Pinto S, Einen M, Simakajornboon N, Han F, Peppard P, Nevsimalova S, Plazzi G, Rye D, Mignot E. The MSLT is Repeatable in Narcolepsy Type 1 But Not Narcolepsy Type 2: A Retrospective Patient Study. J Clin Sleep Med. 2018 Jan 15; 14(1):65-74.
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  17. Scrima L, Emsellem HA, Becker PM, Ruoff C, Lankford A, Bream G, Khayrallah M, Lu Y, Black J. Identifying clinically important difference on the Epworth Sleepiness Scale: results from a narcolepsy clinical trial of JZP-110. Sleep Med. 2017 Oct; 38:108-112 Epub 2017 July 22
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  18. Ruoff C, Bogan RK, Emsellem H, Feldman N, Lankford A, Bream G, Khayrallah M, Lu Y, Carter LP, Black J. Evaluation of the effect of JZP-110 in patients with narcolepsy assessed using the Maintenance of Wakefulness Test censored to 20 minutes. Sleep Med. 2017 Jul; 35:12-16 Epub 2017 Apr 22
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  19. Ruoff CM, Reaven NL, Funk SE, McGaughey KJ, Ohayon MM, Guilleminault C, Black J. High Rates of Psychiatric Comorbidity in Narcolepsy: Findings From the Burden of Narcolepsy Disease (BOND) Study of 9,312 Patients in the United States. J Clin Psychiatry. 2017 Feb; 78 (2):171-176
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  20. Ruoff C, Rye D. The ICSD-3 and DSM-5 guidelines for diagnosing narcolepsy: clinical relevance and practicality. Curr Med Res Opin. 2016 Oct; 32 (10):1611-1622 Epub 2016 July 20
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  21. Ruoff C, Swick TJ, Doekel R, Emsellem HA, Feldman NT, Rosenberg R, Bream G, Khayrallah MA, Lu Y, Black J. Effect of Oral JZP-110 (ADX-N05) on Wakefulness and Sleepiness in Adults with Narcolepsy: A Phase 2b Study. Sleep. 2016 Jul 1; 39 (7):1379-87 Epub 2016 July 01
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  22. Black J, Reaven N, Funk S, McGaughery K, Ohayon M, Guilleminault C, Ruoff C. Medical Comorbidity in Narcolepsy: Findings from the Burden of Narcolepsy Disease (BOND) Study. Sleep Medicine. 2016.
  23. Camacho M, Ruoff CM, Kawai M, Modi R, Arbee J, Hekmat A, Robertson M, Zaghi S, Certal V, Capasso R, Kushida CA. Five-Minute Awake Snoring Test for Determining CPAP Pressures (Five-Minute CPAP Test): A Pilot Study. Sleep Disord. 2016; 2016:7380874 Epub 2016 Jan 11
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  24. Liebenthal J, Valerio J, Ruoff C, Mahowald M. A Case of Rapid Eye Movement Sleep Behavior Disorder in Parkinson Disease Treated With Sodium Oxybate. JAMA Neurol. 2016 Jan; 73 (1):126-7
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  25. Camacho M, Robertson M, Abdullatif J, Certal V, Kram YA, Ruoff CM, Brietzke SE, Capasso R. Smartphone Apps for Snoring. Journal of Laryngology and Otology. 2015 Sep; 3:1-6.
  26. Camacho M, Certal V, Abdullatif J, Zaghi S, Ruoff CM, Capasso R, Kushida CA. Myofunctional Therapy to Treat Obstructive Sleep Apnea: A Systematic Review and Meta-analysis. Sleep. 2015 May 1; 38 (5):669-75 Epub 2015 May 01
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  27. Camacho M, Riaz M, Capasso R, Ruoff CM, Guilleminault C, Kushida CA, Certal V. The effect of nasal surgery on continuous positive airway pressure device use and therapeutic treatment pressures: a systematic review and meta-analysis. Sleep. 2015 Feb 1; 38 (2):279-86 Epub 2015 Feb 01
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  28. Dandekar F, Camacho M, Valerio J, Ruoff CM. Periorbital edema secondary to positive airway pressure therapy. Case Rep Ophthalmol Med. 2015; 2015:126501 Epub 2015 Feb 12
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  29. Goldbart A, Peppard P, Finn L, Ruoff CM, Barnet J, Young T, Mignot E. Narcolepsy and predictors of positive MSLTs in the Wisconsin Sleep Cohort. Sleep. 2014 Jun 1; 37 (6):1043-51 Epub 2014 June 01
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  30. Black J, Reaven NL, Funk SE, McGaughey K, Ohayon M, Guilleminault C, Ruoff C, Mignot E. The Burden of Narcolepsy Disease (BOND) study: health-care utilization and cost findings. Sleep Med. 2014 May; 15 (5):522-9 Epub 2014 Feb 15
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  31. Ruoff C, Black J. Psychiatric Dimensions of Narcolepsy. Psychiatric Times. 2014; 31(1):17-21.
  32. Ruoff C, Guilleminault C. Hypocretin receptor antagonists for insomnia: rationale and clinical data. Clinical Investigation. 2012; 2(6):623-37.
  33. Ruoff C, Cao M, Guilleminault C. Hypocretin antagonists in insomnia treatment and beyond. Curr Pharm Des. 2011; 17 (15):1476-82
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