Joseph L. Blackshear, M.D.

  1. Cardiologist
  • Dr. Blackshear joined the staff of Mayo Clinic Florida as an assistant professor of medicine at the time of its founding in 1986. He has served as the chair of the division of cardiovascular diseases and president of the medical staff among other roles.
  • In the 1990s he was involved in a number of pivotal trials of warfarin and comparators in atrial fibrillation, and founded the idea of atrial appendage exclusion or resection to reduce stroke risk.
  • In 1993 he was promoted to Associate Professor, and in 1999 to Professor of Medicine.
  • His current interests include valvular disease, hypertrophic cardiomyopathy, and the impact of high intravascular shear from cardiac disorders on von Willebrand factor and bleeding.
  • He is the author or coauthor of 116 peer reviewed papers and numerous book chapters and abstracts.
  1. Cardioversion
  2. Transesophageal echocardiogram
  • Bleeding associated with heart valve and muscle disorders
  • Valvular heart disease
  • Hypertrophic cardiomyopathy
  • acquired von Willebrand Syndrome
  1. 1986
    Clinical Fellowship - CardiologyDuke University Medical Center
  2. 1984
    Research Fellowship - MedicineHarvard Medical School
  3. 1982
    Resident - Internal MedicineHennepin County Medical Center
  4. 1980
    Resident - Internal MedicineHennepin County Medical Center
  5. 1979
    Internship - MedicineHennepin County Medical Center
  6. 1978
    MDMayo Medical School, Mayo Clinic College of Medicine
  7. 1974
    BA - AnthropologyUniversity of Minnesota


  1. 1987
    Cardiovascular DiseasesAmerican Board of Internal Medicine
  2. 1982
    Internal MedicineAmerican Board of Internal Medicine

Awards and honors

  1. 2017
    Excellence in Teaching in the Discipline on Cardiovascular Diseases Award Mayo Clinic Florida Medical Residency Program
  2. 2015
    Excellence in Teaching in the Discipline on Cardiovascular Diseases AwardMayo Clinic Florida
  3. 2013
    Department of Medicine Research AwardMayo Clinic Florida
  4. 1999
    Excellence in Teaching in the Discipline on Cardiovascular Diseases AwardInternal Medicine Residency Program, Department of Internal Medicine
  5. 1998
    Educator-of-the-Year NomineeMayo Clinic in Florida

Professional memberships

  1. 2008 - 2010
    ReviewerClinical Trials of Hematide, Affymax, Inc.
  2. 2007 - 2010
    ChairMyocardial Infarction Event Committee, Carotid Revascularization with Endarterectomy or Stenting Trial (CREST), National Heart, Lung, and Blood Institute


Research activities

See a description of research activities.