Proper Use

Drug information provided by: Merative, Micromedex®

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

Tell your doctor if you have Asian relatives, such as Filipino, Chinese, Japanese, Korean, or Taiwanese. You may need a lower dose of this medicine.

This medicine comes with a Medication Guide and patient instructions. Read and follow these instructions carefully. Ask your doctor if you have any questions.

Take this medicine without a meal or with a meal low in calcium (50 milligrams or less).

If you are taking antacids, multivitamins that contain aluminum, calcium, iron, magnesium, selenium, or zinc, or other products high in calcium (more than 50 milligrams of calcium including dairy products, juices, and certain fruits and vegetables), take these at least 4 hours before or 2 hours after eltrombopag.

Swallow the tablet whole. Do not crush, break, or chew it. Do not mix it with food or liquids.

If you are using the oral suspension:

  • Mix the powder with cold water only. Do not use hot water to mix it.
  • After mixing, take it within 30 minutes. If it comes in contact with your skin, wash it right away with soap and water.
  • Use the dosing syringe that comes with the package. The average household teaspoon may not hold the right amount of liquid.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For first-line treatment of severe aplastic anemia:
    • For oral dosage forms (Promacta® suspension or tablets):
      • Adults and children 12 years of age and older—At first, 150 milligrams (mg) once a day for 6 months. Some patients may start at a lower dose. Your doctor may adjust your dose as needed.
      • Children 6 to 11 years of age—At first, 75 mg once a day for 6 months. Some patients may start at a lower dose. Your doctor may adjust your dose as needed.
      • Children 2 to 5 years of age—Dose is based on weight and must be determined by your doctor. At first, 2.5 milligram per kilogram (mg/kg) of body weight once a day for 6 months. Some patients may start at a lower dose. Your doctor may adjust your dose as needed.
      • Children younger than 2 years of age—Use and dose must be determined by your doctor.
  • For refractory severe aplastic anemia:
    • For oral dosage forms (Promacta® suspension or tablets):
      • Adults—At first, 50 milligrams (mg) once a day. Some patients may start at a lower dose. Your doctor may adjust your dose as needed. However, the dose is usually not more than 150 mg per day.
      • Children—Use and dose must be determined by your doctor.
    • For oral dosage form (Alvaiz™ tablets):
      • Adults—At first, 36 milligrams (mg) once a day. Some patients may start at a lower dose. Your doctor may adjust your dose as needed. However, the dose is usually not more than 108 mg per day.
      • Children—Use and dose must be determined by your doctor.
  • For thrombocytopenia with ITP:
    • For oral dosage forms (Promacta® suspension or tablets):
      • Adults and children 6 years of age and older—At first, 50 milligrams (mg) once a day. Some patients may start at a lower dose. Your doctor may adjust your dose as needed. However, the dose is usually not more than 75 mg per day.
      • Children 1 to 5 years of age—At first, 25 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 75 mg per day.
      • Children younger than 1 year of age—Use and dose must be determined by your doctor.
    • For oral dosage form (Alvaiz™ tablets):
      • Adults and children 6 years of age and older—At first, 36 milligrams (mg) once a day. Some patients may start at a lower dose. Your doctor may adjust your dose as needed. However, the dose is usually not more than 54 mg per day.
      • Children younger than 6 years of age—Use and dose must be determined by your doctor.
  • For thrombocytopenia with chronic hepatitis C:
    • For oral dosage forms (Promacta® suspension or tablets):
      • Adults—At first, 25 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 100 mg per day.
      • Children—Use and dose must be determined by your doctor.
    • For oral dosage form (Alvaiz™ tablets):
      • Adults—At first, 18 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 72 mg per day.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Throw away any unused liquid within 30 minutes of mixing it.

Portions of this document last updated: May 01, 2024

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