In the early stages, cancer of the ureter often has no warning signs or symptoms. The first warning sign may be blood in the urine (hematuria). Other symptoms can include pain in the space between the ribs and hip (flank), extreme tiredness, weight loss for no reason, or pain or frequent urination. Because these symptoms can also result from more common conditions, expertise in diagnosing cancer of the ureter is vital.
Examples of risk factors for cancer of the ureter include misuse of pain medication for a long time, tobacco use, long-term industrial chemical exposure, or chronic or repeated urinary infections or inflammation.