Ulcerative Colitis

Clinical Trials

Below is a list of Ulcerative Colitis clinical trials from the clinical trials database at Mayo Clinic.

This list includes only trials about which Mayo researchers choose to publish information. Mayo Clinic may be conducting other trials which are not in this database. Mayo's clinical trials include experimental treatments, often unavailable elsewhere, which frequently lead to improved patient care for people worldwide. Patients should ask their doctor at Mayo about clinical trials appropriate for their situation.

A Phase I Study Using rhuMAb Beta7 for Patients with Ulcerative Colitis
The purpose of this study is to investigate the safety and tolerability of an investigational drug called rhuMAb Beta7 in the treatment of ulcerative colotis (UC) at different dose levels and different routes of administration. The sponsor of the trial is developing rhuMAb Beta7 as a possible treatment to reduce the symptoms associated with UC and Crohn's disease, another inflammatory bowel condition.
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Abatacept for the treatment of subjects with active moderate to severe Ulcerative Colitis
The purpose of this study is to see if the investigational use of abatacept is better than placebo (inactive substance) for the treatment of active Ulcerative Colitis. Abatacept was approved by the United States Food and Drug Administration (FDA) in December 2005 for the treatment of rheumatoid arthritis in the United States and in June 2006 in Canada. The use of abatacept remains investigational for other diseases. An investigational use in one that is not yet approved by the regulatory authorities such as the FDA.

A second purpose of this study is to evaluate the safety (possible side effects) of abatacept in patients with Ulcerative Colitis.
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Golimumab therapy, administered subcutaneously, for patients ulcerative colitis
The main purpose of this study is to assess the effects (good and bad) of golimumab on subjects with ulcerative colitis.
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