Mileage and Driving Directions to Mayo Clinic

Location of Rochester, Minn.

Mileage to Mayo Clinic in Rochester, Minn.

Rochester is located in southeast Minnesota, within driving distance of many metropolitan areas. Below is a list of cities and their mileage from Rochester.

• Chicago — 372 miles
• Des Moines — 215 miles
• Fargo — 325 miles
• Green Bay — 275 miles
• Madison — 205 miles
• Milwaukee — 286 miles
• Minneapolis/St. Paul — 90 miles
• Omaha — 345 miles
• Sioux Falls — 238 miles

Driving directions

See below for driving directions to Mayo Clinic in Rochester, Minn.

From I-90 westbound

To Mayo Clinic's downtown, Rochester campus (Mayo, Gonda and Charlton buildings and Rochester Methodist Hospital)
Take Exit 218 to U.S. Highway 52.
Go north on U.S. Highway 52 to U.S. Highway 63 (Broadway Avenue).
Take Exit 51 to U.S. Highway 63 (Broadway Avenue) north.
Go north on U.S. Highway 63 (Broadway Avenue) to Second Street Southwest.
Turn left onto Second Street Southwest.
Turn right onto Third Avenue Southwest.
Gonda Building patient drop-off is on the right.
Damon Patient/Visitor Parking Ramp is on the left.
Graham Patient/Visitor Parking Ramp is two blocks north.

To Mayo Clinic's Saint Marys campus (Saint Marys Hospital)
Take Exit 218 to U.S. Highway 52.
Go north on U.S. Highway 52.
Take Exit 55B to Second Street Southwest.
Turn right onto Second Street Southwest.
Turn right onto 14th Avenue Southwest to Saint Marys Hospital entrance.

From I-90 eastbound

To Mayo Clinic's downtown, Rochester campus (Mayo, Gonda and Charlton buildings and Rochester Methodist Hospital)
Take Exit 209B to Minnesota State Highway 30 west/U.S. Highway 63 north.
Take U.S. highway 63 north to Second Street Southwest.
Turn left onto Second Street Southwest.
Turn right onto Third Avenue Southwest.
Gonda Building patient drop-off is on the right.
Damon Patient/Visitor Parking Ramp is on the left.
Graham Patient/Visitor Parking Ramp is two blocks north.

To Mayo Clinic's Saint Marys campus (Saint Marys Hospital)
Take Exit 209B to Minnesota State Highway 30 west/U.S. Highway 63 north.
Take U.S. Highway 63 north to U.S. Highway 52 north.
Merge onto U.S. Highway 52 north via the ramp to St. Paul.
Take Exit 55B to Second Street Southwest.
Turn right onto Second Street Southwest.
Turn right onto 14th Avenue Southwest to Saint Marys Hospital entrance.

From U.S. Highway 14 westbound

To Mayo Clinic's downtown, Rochester campus (Mayo, Gonda and Charlton buildings and Rochester Methodist Hospital)
Turn right onto U.S. Highway 63 (Broadway Avenue).
Take U.S. Highway 63 (Broadway Avenue) to Second Street Southwest.
Turn left onto Second Street Southwest.
Turn right onto Third Avenue Southwest.
Gonda Building patient drop-off is on the right.
Damon Patient/Visitor Parking Ramp is on the left.
Graham Patient/Visitor Parking Ramp is two blocks north.

To Mayo Clinic's Saint Marys campus (Saint Marys Hospital)
Turn right onto U.S. Highway 63 (Broadway Avenue).
Take U.S. Highway 63 (Broadway Avenue) to Second Street Southwest.
Turn left onto Second Street Southwest to 14th Avenue Southwest.
Turn left onto 14th Avenue Southwest to Saint Marys Hospital entrance.

From U.S. Highway 14 eastbound

To Mayo Clinic's downtown, Rochester campus (Mayo, Gonda and Charlton buildings and Rochester Methodist Hospital)
Go east on U.S. Highway 14 until it turns into Civic Center Drive.
Turn right onto Fourth Avenue Northwest to Second Street Southwest.
Turn left onto Second Street Southwest.
Turn left onto Third Avenue Southwest.
Gonda Building patient drop-off is on the right.
Damon Patient/Visitor Parking Ramp is on the left.
Graham Patient/Visitor Parking Ramp is two blocks north.

To Mayo Clinic's Saint Marys campus (Saint Marys Hospital)
Go east on U.S. Highway 14 to U.S. Highway 52 south.
Take U.S. Highway 52 south to Second Street Southwest.
Take Exit 55B to Second Street Southwest.
Turn left onto Second Street Southwest.
Turn right onto 14th Avenue Southwest to Saint Marys Hospital entrance.

From U.S. Highway 52 southbound

To Mayo Clinic's downtown, Rochester campus (Mayo, Gonda and Charlton buildings and Rochester Methodist Hospital)
Go south on U.S. Highway 52.
Take Exit 55B to Second Street Southwest.
Turn left onto Second Street Southwest.
Continue on Second Street Southwest to Third Avenue Southwest.
Turn left onto Third Avenue Southwest.
Gonda Building patient drop-off is on the right.
Damon Patient/Visitor Parking Ramp is on the left.
Graham Patient/Visitor Parking Ramp is two blocks north.

To Mayo Clinic's Saint Marys campus (Saint Marys Hospital)
Go south on U.S. Highway 52.
Take Exit 55B to Second Street Southwest.
Turn left onto Second Street Southwest.
Turn right onto 14th Avenue Southwest to Saint Marys Hospital entrance.

From U.S. Highway 52 northbound

To Mayo Clinic's downtown, Rochester campus (Mayo, Gonda and Charlton buildings and Rochester Methodist Hospital)
Go north on U.S. Highway 52.
Take Exit 55B to Second Street Southwest.
Turn right onto Second Street Southwest.
Continue on Second Street Southwest to Third Avenue Southwest.
Turn left onto Third Avenue Southwest.
Gonda Building patient drop-off is on the right.
Damon Patient/Visitor Parking Ramp is on the left.
Graham Patient/Visitor Parking Ramp is two blocks north.

To Mayo Clinic's Saint Marys campus (Saint Marys Hospital)
Go north on U.S. Highway 52 to Second Street Southwest.
Take Exit 55B to Second Street Southwest.
Turn right onto Second Street Southwest.
Turn right onto 14th Avenue Southwest to Saint Marys Hospital entrance.

From U.S. Highway 63 southbound

To Mayo Clinic's downtown, Rochester campus (Mayo, Gonda and Charlton buildings and Rochester Methodist Hospital)
Go south on U.S. Highway 63 (Broadway Avenue) to Second Street Southwest.
Turn right onto Second Street Southwest to Third Avenue Southwest.
Turn right onto Third Avenue Southwest.
Gonda Building patient drop-off is on the right.
Damon Patient/Visitor Parking Ramp is on the left.
Graham Patient/Visitor Parking Ramp is two blocks north.

To Mayo Clinic's Saint Marys campus (Saint Marys Hospital)
Go south on U.S. Highway 63 (Broadway Avenue) to Second Street Southwest.
Turn right onto Second Street Southwest to 14th Avenue Southwest.
Turn left onto 14th Avenue Southwest to Saint Marys Hospital entrance.

From U.S. Highway 63 northbound

To Mayo Clinic's downtown, Rochester campus (Mayo, Gonda and Charlton buildings and Rochester Methodist Hospital)
Go north on U.S. Highway 63 (Broadway Avenue) to Second Street Southwest.
Turn left onto Second Street Southwest to Third Avenue Southwest.
Turn right onto Third Avenue Southwest.
Gonda Building patient drop-off is on the right.
Damon Patient/Visitor Parking Ramp is on the left.
Graham Patient/Visitor Parking Ramp is two blocks north.

To Mayo Clinic's Saint Marys campus (Saint Marys Hospital)
Go north on U.S. Highway 63 (Broadway Avenue) to Second Street Southwest.
Turn left onto Second Street Southwest to 14th Avenue Southwest.
Turn left onto 14th Avenue Southwest to Saint Marys Hospital entrance.