Overview

Transcatheter aortic valve replacement (TAVR) is a minimally invasive procedure to replace a narrowed aortic valve that fails to open properly (aortic valve stenosis). Transcatheter aortic valve replacement is sometimes called transcatheter aortic valve implantation (TAVI).

TAVR may be an option for people who are considered at intermediate or high risk of complications from surgical aortic valve replacement. TAVR may also be indicated in certain people who can't undergo open-heart surgery. The decision to treat aortic stenosis with TAVR is made after consultation with a multidisciplinary group of medical and surgical heart specialists who together determine the best treatment option for each individual.

TAVR can relieve the signs and symptoms of aortic valve stenosis and may improve survival in people who can't undergo surgery or have a high risk of surgical complications.

Mayo Clinic's approach

Feb. 02, 2017
References
  1. Brecker SJD, et al. Transcatheter aortic valve replacement: Indications. http://www.uptodate.com/home. Accessed Aug. 16, 2016.
  2. What is heart valve disease? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/hvd. Accessed Aug. 16, 2016.
  3. What is TAVR? American Heart Association. http://www.heart.org/HEARTORG/Conditions/More/HeartValveProblemsandDisease/What-is-TAVR_UCM_450827_Article.jsp#.VrUe2dj2aDY. Accessed Aug. 16, 2016.
  4. AskMayoExpert. Aortic valve stenosis (adult). Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2016.
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  6. Gaasch WH. Indications for valve replacement in aortic stenosis in adults. http://www.uptodate.com/home. Accessed Aug. 16, 2016.
  7. Mack MJ, et al. Patient selection for transcatheter aortic valve replacement. Journal of the American College of Cardiology. 2013;62:S1.
  8. Gaasch WH, et al. Transcatheter aortic valve replacement: Outcomes and complications. http://www.uptodate.com/home. Accessed Aug. 16, 2016.
  9. Holmes DR, et al. Clinical outcomes at 1 year following transcatheter aortic valve replacement. JAMA. 2015;313:1019.
  10. Barbara Woodward Lips Patient Education Center. Transcatheter aortic valve replacement (TAVR). Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2014.
  11. Barbara Woodward Lips Patient Education Center. Getting ready for heart surgery. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2011.
  12. Agarwal S, et al. Transcatheter aortic valve replacement: Current perspectives and future implications. Heart. 2015;101:169.
  13. Mack MJ, et al. 5-year outcomes of transcatheter aortic valve replacement or surgical aortic valve replacement for high surgical risk patients with aortic stenosis (PARTNER 1): A randomised controlled trial. The Lancet. 2015;385:2477.
  14. Riggin EA. Allscripts EPSi. Mayo Clinic, Rochester, Minn. Aug. 3, 2016.
  15. Brecker SJD, et al. Transcatheter aortic valve replacement: Periprocedural management. http://www.uptodate.com/home. Accessed Oct. 7, 2016.
  16. Reardon MJ, et al. Outcomes in the randomized CoreValve US pivotal high-risk trial in patients with a Society of Thoracic Surgeons risk score of 7% or less. JAMA Cardiology. In press. Accessed Aug. 23, 2016.
  17. Leon MB, et al. Transcatheter or surgical aortic-valve replacement in intermediate-risk patients. The New England Journal of Medicine. 2016;374;1609.
  18. Bisesar BR. The NCDR STS/ACC TVT Registry. Mayo Clinic. Oct. 19, 2016.
  19. Greason KL (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 24, 2016.

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