Splenectomy is generally a safe procedure. But as with any surgery, splenectomy carries the potential risk of complications.

Potential complications include:

  • Bleeding
  • Blood clots
  • Infection
  • Injury to other organs nearby, including your stomach, pancreas and colon

Long-term risk of infection

After spleen removal, you're more likely to contract serious or even life-threatening infections. Following splenectomy, your doctor may recommend you receive a pneumonia vaccine and yearly flu vaccines. In some cases, preventive antibiotics may be recommended as well, especially if you have other conditions that increase your risk of serious infections.

Jul. 20, 2012