Below are current clinical trials.42 studies in Radiation therapy
(open studies only).
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This randomized phase II study aims to investigate whether the addition of bevacizumab to standard corticosteroid therapy results in greater improvement in symptoms and less treatment-induced symptoms compared with standard corticosteroid therapy for patients with symptomatic brain radionecrosis following radiosurgery. It is hypothesized that the addition of bevacizumab to standard care corticosteroids will reduce treatment-induced toxicities and improve neurologic impairments in patients with brain radionecrosis following radiosurgery for brain metastases.
Jacksonville, Fla., Rochester, Minn., La Crosse, Wis., Albert Lea, Minn., Mankato, Minn.
RATIONALE: Giving radiation therapy that uses a 3-dimensional (3-D) image of the tumor to help focus thin beams of radiation directly on the tumor, and giving radiation therapy in higher doses over a shorter period of time, may kill more tumor cells and have fewer side effects. Monoclonal antibodies, such as cetuximab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. It is not yet known whether radiation therapy is more effective when given alone or together with cetuximab in treating patients with head and neck cancer that has been removed by surgery.
PURPOSE: This randomized phase III trial is studying radiation therapy to see how well it works compared with radiation therapy given together with cetuximab in treating patients who have undergone surgery for locally advanced head and neck cancer.
Aug. 01, 2017
- Radiation therapy and you: Support for people with cancer. National Cancer Institute. https://www.cancer.gov/publications/patient-education/radiation-therapy-and-you. Accessed April 2, 2017.
- External beam therapy (EBT). RadiologyInfo.org. https://www.radiologyinfo.org/en/info.cfm?pg=ebt. Accessed April 2, 2017.
- Gunderson LL, et al. Intensity-modulated and image-guided radiation therapy. In: Clinical Radiation Oncology. 4th ed. Philadelphia, Pa.: Saunders Elsevier; 2016. https://www.clinicalkey.com. Accessed Jan. 4, 2017.
- Riggin ER. Allscripts EPSi. Mayo Clinic, Rochester, Minn. Jan. 31, 2017.