How you prepare

To prepare for your prostate biopsy, your urologist may have you:

  • Provide a urine sample to analyze for a urinary tract infection. If you have a urinary tract infection, your prostate biopsy will likely be postponed while you take antibiotics to clear the infection.
  • Stop taking medication that can increase the risk of bleeding — such as warfarin (Coumadin), aspirin, ibuprofen (Advil, Motrin IB, others), and certain herbal supplements — for several days before the procedure.
  • Do a cleansing enema at home before your biopsy appointment.
  • Take antibiotics 30 to 60 minutes before your prostate biopsy to help prevent infection from the procedure.