If you're interested in noninvasive prenatal testing, talk to your health care provider about its availability. Also, consider checking to see if your health insurance covers the cost of noninvasive prenatal testing.
Before you undergo noninvasive prenatal testing, your health care provider or a genetic counselor will explain the possible results and what they might mean for you and your baby. Be sure to discuss any questions or concerns you have about the testing process.
Feb. 23, 2013
- National Society of Genetic Counselors Public Policy Committee, et al. Noninvasive prenatal testing/noninvasive prenatal diagnosis: The position of the National Society of Genetic Counselors. National Society of Genetic Counselors. http://www.nsgc.org/Advocacy/PositionStatements/tabid/107/Default.aspx. Accessed Dec. 7, 2012.
- Allyse M, et al. Cell-free fetal DNA testing for fetal aneuploidy and beyond: Clinical integration challenges in the US context. Human Reproduction. 2012;27:3123.
- Wright CF, et al. Non-invasive prenatal diagnostic test accuracy for fetal sex using cell-free DNA a review and meta-analysis. BMC Research Notes. 2012;5:476.
- Devaney SA, et al. Noninvasive fetal sex determination using cell-free fetal DNA: A systematic review and meta-analysis. Journal of the American Medical Association. 2011;306:627.
- Chiu RWK, et al. Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: Large scale validity study. British Medical Journal. 2011;342:c7401.
- Shulman LP. One small step and one giant leap for noninvasive prenatal screening: An editorial. American Journal of Obstetrics and Gynecology. 2011;204:183.
- Ehrich M, et al. Noninvasive detection of trisomy 21 by sequencing of DNA in maternal blood: A study in a clinical setting. American Journal of Obstetrics and Gynecology. 2011;204:205e1.
- Palomaki GE, et al. DNA sequencing of maternal plasma to detect Down syndrome: An international clinical validation study. Genetics in Medicine. 2011;13:913.
- Frequently asked questions. Pregnancy FAQ133. Routine tests in pregnancy. American College of Obstetrics and Gynecology. http://www.acog.org/~/media/For%20Patients/faq133.pdf?dmc=1&ts=20121207T1430460501. Accessed Dec. 7, 2012.
- Down syndrome overview. National Institute of Child Health & Human Development. http://www.nichd.nih.gov/health/topics/down/Pages/default.aspx. Accessed Dec. 7, 2012.
- Sehnert AJ, et al. Optimal detection of fetal chromosomal abnormalities by massively parallel DNA sequencing of cell-free fetal DNA from maternal blood. Clinical Chemistry. 2011;57:1042.
- What is Down syndrome? National Down Syndrome Society. http://www.ndss.org/Down-Syndrome/What-Is-Down-Syndrome/. Accessed Dec. 7, 2012.
- Diagnostic tests for birth defects. American College of Obstetrics and Gynecology. http://www.acog.org/Resources_And_Publications/Patient_Education_Pamphlets/Files/Diagnostic_Tests_for_Birth_Defects. Accessed Dec. 7, 2012.
- Rijinders RJP, et al. Clinical applications of cell-free fetal DNA from maternal plasma. Obstetrics and Gynecology. 2004;103:157.
- Wick Myra J (expert opinion). Mayo Clinic, Rochester, Minn. Dec. 22, 2012.
- The American College of Obstetricians and Gynecologists Committee on Genetics and the Society for Maternal-Fetal Medicine Publications Committee. Committee Opinion No. 545: Title of committee opinion. Obstetrics & Gynecology. 2012;120:1532.