New medication options

Liver transplant research at Mayo Clinic Liver transplant research at Mayo Clinic

Mayo Clinic scientists, doctors and surgeons are actively engaged in developing new technologies, treatments and techniques to make transplants safer and available to more people.

Mayo Clinic scientists, doctors and surgeons are actively engaged in research to make liver transplants safer and available to more people and improve results after transplant by developing new medication options.

Current research topics include:

  • Bioartificial liver. This innovation helps people cope as they await a donor liver. Developed by Mayo Clinic doctors and researchers, new bioartificial livers use living cells from pig livers to filter a patient's blood in a process similar to that of kidney dialysis. The device is being tested before it becomes available in clinics and hospitals.
  • Immunosuppressive medications. This research examines the effect of antibody-mediated injury in liver-kidney transplants and how doing a multiorgan transplant may actually result in better outcomes.
  • Cell therapies for liver disease. This research offers potential new treatments for several liver diseases and may improve the success of liver transplantation.

Read more about the many liver transplant research studies supported by the Transplant Research Center.

Sept. 24, 2016
References
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  4. Questions & answers for transplant candidates about MELD and PELD. United Network for Organ Sharing. http://www.unos.org/docs/MELD_PELD. Accessed May 28, 2014.
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  15. Taner T, et al. Decreased chronic cellular and antibody-mediated injury in the kidney following simultaneous liver-kidney transplantation. Kidney International. 2016;89:909.
  16. De Assuncao TM, et al. Development and characterization of human-induced pluripotent stem cell-derived cholangiocytes. Laboratory Investigation. 2015;95:684.
  17. Croome KP, et al. The use of donation after cardiac death allografts does not increase recurrence of hepatocellular carcinoma. American Journal of Transplantation. 2015;15:2704.
  18. Tincani G, et al. Operative risks of domino liver transplantation for the familial amyloid polyneuropathy liver donor and recipient: A double analysis. American Journal of Transplantation. 2011;11:750.
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  20. Scientific Registry of Transplant Recipients. http://www.srtr.org/default.aspx. Accessed April 11, 2016.
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