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Below are current clinical trials.
Filter this list of studies by location, status and more.
The purpose of this study is to compare the outcome following manipulation under anesthesia for stiffness with one group receiving IV dexamethasone and oral celecoxib at the time of manipulation to a control group receiving manipulation alone. Measured outcomes will include pain, range of motion, as well as subjective outcome scores.
The purpose of this study is to assess the impact of a whole food plant-based diet on blood sugar control in diabetic patients versus a control group on the American Diabetics Association diet before having a total hip, knee, or shoulder replacement surgery.
The prevalence of chronic pain following total knee replacement has been under studied. In recent years, the perioperative use of multimodal analgesic strategies including regional anesthetic techniques has substantially improved early postoperative pain management. However, it is not clear that these improvements in perioperative care have reduced the frequency of chronic pain post-total knee replacement. This study will conduct a cross sectional study to determine the prevalence of chronic knee pain following total knee replacement up to 5 years postoperatively. This study will also identify risk factors, such as smoking, depression, and pain problems elsewhere as predictors of chronic knee pain after knee replacement.
The purpose of this study is to find out whether knee joint fluid (synovial fluid) contains substances which may interfere with laboratory tests not normally done on synovial fluid.
This study is being conducted to determine gene and protein expression profiles (i.e. which genes and proteins are turned off and on) of those with a possibility of developing osteolysis, infection, arthrofibrosis or metallosis of their THA/TKA.
To determine the optimal dosing regimen and route of administration of tranexamic acid (TXA) [single dose intravenous (IV), double dose intravenous, intravenous + topical, and oral repeated dosing] to minimize post-operative blood loss and transfusion requirements following revision total knee arthroplasty (RTKA).
The purpose of this study is to learn why there are differences between those who develop stiff joints and those who do not by examining the genes responsible for joint contractures in people who have had total joint surgery.
The purpose of this study is to learn the effects of synovial fluid, a clear thick joint lubricant, on joint cartilage tissue and the development of osteoarthritis
The purpose of this study is to evaluate and compare implant kinematics of conventional mechanically aligned and anatomically aligned total knee arthroplasties (TKA) at 1 year post-operatively.
The purpose of this study is to determine the best dosing plan and route of administration of tranexamic acid to minimize post-operative blood loss and transfusion requirements after a redo of a total knee replacement surgery.
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