Nov. 25, 2014
Below are current clinical trials.1 studies in Hyperbaric oxygen therapy
(open studies only).
Filter this list of studies by location, status and more.
Hyperbaric Oxygen for Ulcerative Colitis
Study type: Interventional What is this?
Describes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
About this study
The investigators aim to prospectively study the feasibility and clinical impact of hyperbaric oxygen therapy in acute hospitalized moderate to severe ulcerative colitis flares as an adjunct to standard medical treatment. Specifically, we will investigate the impact of hyperbaric oxygen therapy on clinical response/remission and serum and mucosal inflammatory markers. The investigators expect that hyperbaric oxygen therapy will improve patient responsiveness to steroids and avoid progression to second line therapy during hospitalization.
Participating Mayo Clinic locations
Study statuses change often. Please contact us for help.
Print study details
- Rochester, Minnesota: 13-008673
NCT ID: NCT02144350
Sponsor Protocol Number: HBO-UC
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- Bennett MH, et al. Hyperbaric oxygen therapy for acute ischaemic stroke. Cochrane Database of Systematic Reviews. http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004954.pub2/abstract. Accessed May 20, 2014.
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- Dauwe PB, et al. Does hyperbaric oxygen therapy work in facilitating acute wound healing: A systematic review. Plastic & Reconstructive Surgery Journal. 2014;133:208e.
- Bennett MH, et al. Hyperbaric oxygen therapy for late radiation tissue injury. Cochrane Database of Systematic Reviews. http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD005005.pub3/abstract. Accessed July 25, 2014.
- Bennett MH, et al. Hyperbaric oxygen for idiopathic sudden sensorineural hearing loss and tinnitus. Cochrane Database of Systematic Reviews. http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004739.pub4/abstract. Accessed July 25, 2014.
- Riggin EA. Decision Support System. Mayo Clinic, Rochester, Minn. June 25, 2014.
- Tharangini Raveenthiraraja MS. Hyperbaric oxygen therapy: A review. International Journal of Pharmacy and Pharmaceutical Sciences. 2013;5:52.
- Barbara Woodward Lips Patient Education Center. Hyperbaric Oxygen Therapy. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2010.
- Casey DP, et al. Vasoconstrictor responsiveness during hyperbaric hyperoxia in contracting human muscle. Journal of Applied Physiology. 2013;114:217.
- Murad MH, et al. Using GRADE for evaluating the quality of evidence in hyperbaric oxygen therapy clarifies evidence limitations. Journal of Clinical Epidemiology. 2014;67:65.
- Rajagopalan G, et al. Is HOT a cool treatment for type 1 diabetes? Diabetes. 2012;61:1664.
- Hyperbaric oxygen therapy: Don't be misled. U.S. Food and Drug Administration. http://www.fda.gov/forconsumers/consumerupdates/ucm364687.htm. Accessed Aug. 20, 2014.
- Liu R, et al. Systematic review of the effectiveness of hyperbaric oxygenation therapy in the management of chronic diabetic foot ulcers. Mayo Clinic Proceedings. 2013;88:166.
- Indications for hyperbaric oxygen therapy. Undersea & Hyperbaric Medical Society. http://membership.uhms.org/?page=Indications. Accessed Aug. 21, 2014.
- Millman MP (expert opinion). Mayo Clinic, Rochester, Minn. Oct. 15, 2014.