Side effects of hormone therapy for breast cancer include:

  • Hot flashes
  • Vaginal discharge
  • Vaginal dryness or irritation
  • Fatigue
  • Nausea
  • Joint and muscle pain
  • Impotence in men with breast cancer

Less common, more-serious side effects of hormone therapy may include:

  • Blood clots in veins
  • Endometrial cancer or uterine cancer
  • Cataracts
  • Stroke
  • Osteoporosis
  • Heart disease