Holmium laser enucleation of the prostate (HoLEP) is a treatment for an enlarged prostate (benign prostatic hyperplasia).

During HoLEP, a laser is used to precisely remove the obstructive portion of the prostate, similar to open surgery without the need for incisions. A separate instrument called a morcellator is then used to cut the prostate tissue into easily removable fragments. With HoLEP, surgeons remove the entire portion of the prostate gland that can block urine flow, which improves urinary symptoms and provides a lasting solution as there is nothing to grow back following this procedure.

HoLEP is an effective and less invasive alternative to older, more traditional methods of removing prostate obstructions. In addition, HoLEP preserves removed tissue for microscopic examination. After the procedure, Mayo Clinic pathologists can examine the tissue for the presence of other conditions, including prostate cancer.

Researchers continue to study long-term results of prostate laser surgery, including HoLEP.

Read more about enlarged prostate and prostate laser surgery.

  • Expertise and experience. A number of Mayo Clinic urologic surgeons have the specialized skills and training required for holmium laser prostate surgery. Together they do more than 200 HoLEP procedures a year.
  • Help choosing the best option. Your doctor's advice about the best treatment for you will be based on expert knowledge of and experience with all treatment options for enlarged prostate.
  • Research. Mayo Clinic doctors continue to refine HoLEP and other laser procedures while contributing to advances in laser technology and equipment.

Mayo Clinic in Rochester, Minn., is ranked among the Best Hospitals for urology by U.S. News & World Report. Mayo Clinic in Scottsdale, Ariz., and Mayo Clinic in Jacksonville, Fla., are ranked high performing for urology by U.S. News & World Report.

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Specialists in urology at Mayo Clinic in Arizona offer laser PVP.

For appointments or more information, call the Central Appointment Office at 800-446-2279 (toll-free) 8 a.m. to 5 p.m. Mountain Standard Time, Monday through Friday or complete an online appointment request form.

Specialists in urology at Mayo Clinic in Florida offer laser PVP.

For appointments or more information, call the Central Appointment Office at 904-953-0853 8 a.m. to 5 p.m. Eastern time, Monday through Friday or complete an online appointment request form.

Specialists in urology at Mayo Clinic in Minnesota offer laser PVP. The treatment was pioneered by doctors at Mayo Clinic in Minnesota.

For appointments or more information, call the Central Appointment Office at 507-538-3270 7 a.m. to 6 p.m. Central time, Monday through Friday or complete an online appointment request form.

See information on patient services at the three Mayo Clinic locations, including transportation options and lodging.

Amy E. Krambeck, M.D., of Mayo Clinic in Minnesota, is part of a team of researchers at Mayo Clinic evaluate diagnostic methods, medical therapies, surgical techniques and new technologies in an effort to continually improve the treatment of benign prostatic hyperplasia and prostate cancer. Mayo Clinic's Urology Department maintains an extensive registry of data about the results of treatment of all patients, which helps Mayo Clinic doctors evaluate the effectiveness of treatments and guide treatment decisions.

Publications

See a list of publications by Mayo Clinic doctors on holmium laser enucleation of the prostate (HoLEP) on PubMed, a service of the National Library of Medicine.

Jun. 07, 2013