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Below are current clinical trials.
Filter this list of studies by location, status and more.
Describes the nature of a clinical study. Types include:
This study will use a 22 gene pharmacogenomics panel on 30 children with persistent Gastroesophageal Reflux Disease (GERD) who have not responded to therapy.
Study statuses change often. Please contact us for help.
Open for enrollment
The goal of this study is to examine the current and (potential) future therapeutic relevance of pharmacogenomics (PGx) testing for a group of patients in order to improve patient clinical care at Mayo Clinic with more effective and efficient prescribing of medications.
This study is being done to determine whether there are differences in hereditary information (genes) in people who have migraine and people who do not have migraine. Migraine is a disorder of the brain in which people have repeated attacks of severe headache, nausea, vomiting, light and sound sensitivity and in some cases, period during which the lose vision, have numbness and tingling and/or cannot speak normally. We are also interested in determining how genetic factors might help to predict what type preventative treatment a given migraine sufferer might respond to.
The purpose of this study is to perform RNA (genetic) sequencing on biopsies taken from the esophagus of adult patients who have active eosinophilic esophagitis, and look for potential therapeutic targets.
The purpose of this study is to identify the epigenetic profiles associated with scoliosis progression.
A group of doctors and scientists led by Dr. Fergus Couch at the Mayo Clinic in Rochester, Minnesota, are conducting this study to advance our understanding of how breast cancer is inherited through families. Genetic testing of breast cancer genes is often done to find the cause of breast cancer tracking through families. Testing often identifies deleterious (cancer causing) mutations and Variants of Uncertain Significance (VUS), that may or may not cause breast cancer. Because of uncertainties about the meaning of many of these results, patients and their family members often cannot benefit from the knowledge that they have one of these mutations. In this study we aim to establish the risks of cancer for deleterious mutations and VUS in each of the clinically tested breast cancer genes, so that families and their health care providers can better manage their risk of breast cancer. To answer these questions, we plan to use mutation results from genes currently included on genetic testing panels for breast cancer, along with information on the history of cancer in families and on breast cancer risk factors collected using a questionnaire.
Contact us for the latest status
The study will be performed in two phases: Phase I will be performed for biologic validation of marker candidates from a discovery cohort and phase II will be performed to evaluate the discrimination (sensitivity/specificity) of best candidate markers when assayed from blood of cases with CAP and controls without history of cancer.
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