Deep brain stimulation involves implanting electrodes within certain areas of your brain. These electrodes produce electrical impulses that regulate abnormal impulses. Or, the electrical impulses can affect certain cells and chemicals within the brain.
The amount of stimulation in deep brain stimulation is controlled by a pacemaker-like device placed under the skin in your upper chest. A wire that travels under your skin connects this device to the electrodes in your brain.
Deep brain stimulation is used to treat a number of neurological conditions, such as:
- Essential tremor
- Parkinson's disease
- Tourette syndrome
- Chronic pain
- Obsessive compulsive disorder
Deep brain stimulation is also being studied as an experimental treatment for major depression, stroke recovery, addiction and dementia. Clinical trials may be available to candidates for deep brain stimulation.
Mayo Clinic's approach
Nov. 11, 2015
- Miocinovic S, et al. History, applications, and mechanisms of deep brain stimulation. JAMA Neurology. 2013;70:163.
- Karas PJ, et al. Deep brain stimulation: A mechanistic and clinical update. Neurosurgical Focus. 2013;35:1.
- Brunicardi FC, et al., eds. Neurosurgery. In: Schwartz's Principles of Surgery. 9th ed. New York, N.Y.: The McGraw-Hill Companies; 2010. http://www.accessmedicine.com. Accessed Aug. 31, 2015.
- Cleary DR, et al. Deep brain stimulation for psychiatric disorders: Where are we now. Neurosurgical Focus. 2015;38:1.
- Deep brain stimulation for Parkinson's disease. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/deep_brain_stimulation/deep_brain_stimulation.htm. Accessed Sept. 1, 2015.
- Fenoy AJ, et al. Risks of common complications in deep brain stimulation surgery: Management and avoidance. Journal of Neurosurgery. 2014;120:132.
- Tarsy D. Surgical treatment of Parkinson disease. http://www.uptodate.com/home. Accessed Aug. 28, 2015.
- Venkatraghavan L. Anesthesia for patients having deep brain stimulator implantation. http://www.uptodate.com/home. Accessed Aug. 28, 2015.
- Timmermann L, et al. Multiple-source current steering in subthalamic nucleus deep brain stimulation for Parkinson’s disease (the VANTAGE study): A non-randomised, prospective, multicentre, open-label study. The Lancet Neurology. 2015;14:693.
- Krack P, et al. Deep brain stimulation: From neurology to psychiatry? Trends in Neurosciences. 2010;33:474.
- Riggs EA. Allscripts EPSi. Mayo Clinic, Rochester, Minn. Oct. 6, 2015.