Dec. 18, 2014
Below are current clinical trials.1 studies in Carotid endarterectomy
(open studies only).
Filter this list of studies by location, status and more.
Jacksonville, Fla., Rochester, Minn.
Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial
Study type: Interventional What is this?
Describes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
About this study
Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of carotid revascularization and intensive medical management versus medical management alone in patients with asymptomatic high-grade carotid stenosis. One trial will randomize patients in a 1:1 ratio to endarterectomy versus no endarterectomy and another will randomize patients in a 1:1 ratio to carotid stenting with embolic protection versus no stenting. Medical management will be uniform for all randomized treatment groups and will be centrally directed.
Participating Mayo Clinic locations
Study statuses change often. Please contact us for help.
Print study details
- Jacksonville, Florida: 14-009101
- Rochester, Minnesota: 14-009101
NCT ID: NCT02089217
Sponsor Protocol Number: CREST-2
- What is carotid artery disease? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/catd/. Accessed Oct. 3, 2014.
- What is carotid endarterectomy? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/carend/. Accessed Oct. 3, 2014.
- Mohler ER, et al. Carotid endarterectomy. http://www.uptodate.com/home. Accessed Oct. 3, 2014.
- Mohler ER, et al. Management of asymptomatic carotid atherosclerotic disease. http://www.uptodate.com/home. Accessed Oct. 22, 2014.
- Riggin EA. Decision Support System. Mayo Clinic, Rochester, Minn. Oct. 7, 2014.