Gamma Knife radiosurgery is a type of radiation therapy used to treat tumors, vascular malformations and other abnormalities in the brain.

Gamma Knife radiosurgery, like other forms of stereotactic radiosurgery (SRS), is not surgery in the traditional sense because there is no incision.

Instead, Gamma Knife radiosurgery uses specialized equipment to focus about 200 tiny beams of radiation on a tumor or other target with submillimeter accuracy. Although each beam has very little effect on the brain tissue it passes through, a strong dose of radiation is delivered to the place where all the beams meet.

The precision of brain stereotactic radiosurgery results in minimal damage to healthy tissues surrounding the target.

Gamma Knife radiosurgery is usually a one-time therapy completed in a single day.

Sept. 14, 2016
  1. Stereotactic radiosurgery overview. International RadioSurgery Association. http://www.irsa.org/radiosurgery.html. Accessed May 26, 2016.
  2. Gamma Knife surgery. International RadioSurgery Association. http://www.irsa.org/gamma_knife.html. Accessed May 26, 2016.
  3. Stereotactic radiosurgery. American Association of Neurological Surgeons. http://www.aans.org/Patient%20Information/Conditions%20and%20Treatments/Stereotactic%20Radiosurgery.aspx. Accessed May 26, 2016.
  4. Chen CC, et al. Stereotactic cranial radiosurgery. http://www.uptodate.com/home. Accessed May 26, 2016.
  5. Stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). Radiological Society of North America. http://www.radiologyinfo.org/en/info.cfm?PG=stereotactic. Accessed May 26, 2016.
  6. Arteriovenous malformations and other vascular malformations of the central nervous system fact sheet. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/avms/detail_avms.htm. Accessed May 26, 2016.
  7. NINDS trigeminal neuralgia information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/trigeminal_neuralgia/trigeminal_neuralgia.htm. Accessed May 26, 2016.
  8. Vestibular schwannoma (acoustic neuroma) and neurofibromatosis. National Institute on Deafness and Other Communication Disorders. http://www.nidcd.nih.gov/health/hearing/pages/acoustic_neuroma.aspx. Accessed May 26, 2016.
  9. Gamma Knife. Radiological Society of North America. http://www.radiologyinfo.org/en/info.cfm?pg=gamma_knife. Accessed May 26, 2016.
  10. NINDS pituitary tumors information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/pituitary_tumors/pituitary_tumors.htm. Accessed May 26, 2016.
  11. Ballonoff A. Acute complications of cranial irradiation. http://www.uptodate.com/home. Accessed May 26, 2016.
  12. A typical treatment day. International RadioSurgery Association. http://www.irsa.org/treatment.html. Accessed May 26, 2016.
  13. Neurological diagnostic tests and procedures. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/misc/diagnostic_tests.htm. Accessed May 26, 2016.
  14. Link MJ (expert opinion). Mayo Clinic, Rochester, Minn. June 27, 2016.