What you can expect

Before the procedure

Most people tolerate the injection discomfort well. But you may want your skin to be numbed beforehand, especially if your palms or soles are being treated for excessive sweating. Your doctor might use one or more of various methods available to numb the area, such as topical anesthesia, ice and vibration anesthesia, which uses massage to reduce discomfort.

During the procedure

Your doctor uses a thin needle to inject tiny amounts of botulinum toxin into your skin or muscles. The number of injections needed depends on many factors, including the extent of the area being treated. Botox injections are usually done in a doctor's office.

After the procedure

Expect to resume your normal daily activities right after the procedure. Take care, though, not to rub or massage the treated areas. This can cause the toxin to migrate to a different area.

March 11, 2016
  1. Carruthers J, et al. Overview of botulinum toxin for cosmetic injections. http://www.uptodate.com/home. Accessed Nov. 25, 2015.
  2. Botox medication guide. U.S. Food and Drug Administration. http://www.fda.gov/downloads/Drugs/DrugSafety/UCM176360.pdf. Accessed Nov. 25, 2015.
  3. AskMayoExpert. Spasticity. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2014.
  4. Avram MR, et al., eds. Injectables. In: Procedural Dermatology. New York, N.Y.: McGraw-Hill Education; 2015.
  5. FDA approves Botox to treat overactive bladder. U.S. Food and Drug Administration. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm336101.htm. Accessed Nov. 25, 2015.
  6. AskMayoExpert. Periocular spasm. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2015.
  7. Riggin EA. Allscripts EPSi. Mayo Clinic, Rochester, Minn. Dec. 10, 2015.