A biophysical profile is used to evaluate and monitor a baby's health. The goal of a biophysical profile is to prevent pregnancy loss and detect fetal hypoxia — when the baby is deprived of an adequate oxygen supply — early enough so that the baby can be delivered and not sustain permanent damage.
The test is most commonly done when there's an increased risk of pregnancy loss. Your health care provider will determine the necessity and timing of a biophysical profile based on whether your baby could survive if delivered early, the severity of your condition and the risk of pregnancy loss.
Your health care provider might initially recommend a modified biophysical profile — a simplified version of the test that includes a nonstress test and assesses amniotic fluid through ultrasound. Your health care provider will then use the results to determine whether you need a full biophysical profile, which also measures a baby's breathing, movements and muscle tone.
Your health care provider might recommend a biophysical profile if you have:
- A multiple pregnancy with certain complications
- An underlying medical condition, such as diabetes or heart disease
- A pregnancy that has extended two weeks past your due date (postterm pregnancy)
- A history of pregnancy loss or previous pregnancy complications
- A baby who has decreased fetal movements or possible fetal growth problems
- Preterm premature rupture of the membranes — when the fluid-filled membrane that surrounds and cushions the baby during pregnancy (amniotic sac) leaks or breaks before week 37 of pregnancy
- Too much amniotic fluid (polyhydramnios) or low amniotic fluid volume (oligohydramnios)
- Rh (rhesus) sensitization — a potentially serious condition that can occur when your blood group is Rh negative and your baby's blood group is Rh positive
- Worrisome results from other prenatal tests
Your health care provider might also recommend a biophysical profile if you're between 40 and 42 weeks pregnant. The benefits of having the test done during this period, however, aren't clear.
Your health care provider might recommend that you have a biophysical profile once a week, twice a week or, rarely, even more frequently — depending on your health condition — until you give birth.
March 05, 2015
- Manning FA. The fetal biophysical profile. http://www.uptodate.com/home. Accessed Jan. 29, 2015.
- Signore C, et al. Overview of antepartum fetal surveillance. http://www.uptodate.com/home. Accessed Jan. 29, 2015.
- Frequently asked questions. Pregnancy FAQ098. Special tests for monitoring fetal health. American College of Obstetricians and Gynecologists. http://www.acog.org/Patients/FAQs/Special-Tests-for-Monitoring-Fetal-Health. Accessed Jan. 29, 2015.
- Gabbe SG, et al. Antepartum fetal evaluation. In: Obstetrics: Normal and problem pregnancies. 6th ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.clinicalkey.com. Accessed Jan. 29, 2015.
- Cunningham FG, et al. Fetal assessment. In: Williams Obstetrics. 24th ed. New York, N.Y.: The McGraw-Hill Companies; 2014. http://accessmedicine.com. Accessed Nov. 15, 2011.
- Young BK. Nonstress test and contraction stress test. http://www.uptodate.com/home. Accessed Jan. 29, 2015.
- Taking a close look at ultrasound. U.S. Food and Drug Administration. http://www.fda.gov/downloads/ForConsumers/ConsumerUpdates/UCM095487.pdf. Accessed
- Lalor JG, et al. Biophysical profile for fetal assessment in high risk pregnancies. Cochrane Database of Systematic Reviews. http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD000038.pub2/abstract. Accessed Jan. 29, 2015.
- American College of Obstetricians and Gynecologists (ACOG) Committee on Practice Bulletins — Obstetrics. ACOG Practice Bulletin No. 146: Management of late-term and postterm pregnancies. Obstetrics & Gynecology. 2014;124:390.
- Oyelese Y, et al. The uses and limitations of the fetal biophysical profile. Clinics in Perinatology. 2011;38:47.