The Department of Orthopedic Surgery at Mayo Clinic has long been involved in research advances in orthopedic surgery, including how to alleviate suffering from various ankle and foot conditions. Currently, 24 funded investigators, many of them active clinicians, with nearly $7 million in annual funding, are doing research in 10 basic research laboratories. They also are conducting clinical trials and other clinical research into virtually every aspect of musculoskeletal pathology.

The Biomechanics and Motion Analysis Laboratories in the Department of Orthopedic Surgery use gait analysis, prosthesis evaluation, strength testing and other testing to evaluate a patient's ankle treatment. Foot and ankle specialists in the laboratory test patients in a motion lab to determine which treatment will be most effective for their condition.