Urine odor is related to the volume and concentration of a variety of substances excreted by the kidneys. Normally, urine that contains a lot of water has little to no odor. If your urine becomes highly concentrated — a high level of waste products with little water — urine odor may have a strong ammonia smell.
Many foods and medications, such as asparagus or certain vitamins, can affect the odor of urine. Sometimes, unusual urine odor may indicate a medical condition or disease, such as:
- Bladder infection
- Cystitis (bladder inflammation)
- Diabetic ketoacidosis (high levels of blood acids called ketones)
- Gastrointestinal-bladder fistula (abnormal connection between the intestines and bladder)
- Maple syrup urine disease (rare genetic disease that causes difficulty breaking down certain amino acids)
- Metabolic disorder (a problem with the way your body converts the foods you eat into energy)
- Type 2 diabetes (uncontrolled)
- Urinary tract infection (UTI)
April 23, 2014
Causes shown here are commonly associated with this symptom. Work with your doctor or other health care professional for an accurate diagnosis.
- Brunzel NA. Fundamentals of urine and body fluid analysis. 3rd ed. St. Louis, Mo.: Elsevier Saunders; 2013:97.
- McPherson RA, et al. Henry's Clinical Diagnosis and Management by Laboratory Methods. 22nd ed. Philadelphia. Pa.: Saunders Elsevier; 2011. https://www.clinicalkey.com. Accessed Aug. 5, 2013.
- Bope ET, et al. Conn's Current Therapy. Philadelphia, Pa.: Saunders Elsevier; 2013. http://www.clinicalkey.com. Accessed Aug. 5, 2013.
- Shirasu M, et al. The scent of disease: Volatile organic compounds of the human body related to disease and disorder. The Journal of Biochemistry. 2011;150:257.