Addison's disease occurs when your adrenal glands produce insufficient amounts of certain important hormones. Treatment may include taking corticosteroids.
Alcohol can severely damage your liver — even moderate drinkers aren't immune. Learn more about this serious liver disease.
C. difficile can be a life-threatening infection. It typically develops when antibiotics destroy other bacteria in your intestines, allowing C. difficile to flourish.
Carcinoid tumors are rare, slow-growing cancerous tumors that most often occur in the gastrointestinal tract or in the lungs.
Celiac disease is an immune reaction to gluten, a protein found in certain foods. As a result, the body is unable to absorb some important nutrients.
Chronic lymphocytic leukemia is a cancer of the blood and bone marrow. Unlike other cancers, this form of leukemia doesn't always initially require treatment.
Chronic myelogenous leukemia (CML) is a rare type of blood cancer. New treatments may be improving the prognosis for many people with CML.
Churg-Strauss syndrome is a rare disorder marked by blood vessel inflammation that affects organs throughout the body. Asthma is the most common sign.
Colon cancer and rectal cancer combined are the second-leading cause of cancer-related deaths in the United States. Regular screening tests can help reduce your risk.
Congenital adrenal hyperplasia is a genetic condition affecting the adrenal glands and interfering with normal growth and development in boys and girls.
Cryptosporidium infection may cause diarrhea in healthy people, but for people with HIV/AIDS and weakened immune systems, the illness can cause serious complications.
Diabetes affects how your body uses blood sugar. Too much blood sugar over long periods can cause serious health problems, but treatments are available.
Diabetes insipidus is a rare condition characterized by intense thirst and the excretion of large amounts of urine.
Reduce your risk of esophageal cancer by eating more fruits and vegetables.
Fibromuscular dysplasia is a rare, but treatable, condition in which the arteries to your kidneys, brain or abdomen narrow, reducing blood flow to your organs.
Giant cell arteritis causes inflammation in your arteries, particularly those in your head. Early treatment often relieves symptoms and prevents vision loss, a serious complication.
Giardia infection is a common waterborne illness. Learn the symptoms and reduce your risk.
Hyperthyroidism occurs when your thyroid gland produces too much of the hormone thyroxine — speeding up your metabolism and sometimes leading to serious complications.
In hypopituitarism, your pituitary gland produces too little — or none — of one or more hormones. Disruption of any number of routine body functions can result.
Intestinal ischemia occurs when the blood supply to your digestive system is reduced. Abdominal pain is a common symptom. Several treatment options are available.
The risk of liver cancer may be reduced by protecting yourself from serious liver diseases such as cirrhosis and hepatitis B and C.
Smoking increases your risk of lung cancer. Quit now and reduce your risk.
Mesothelioma is a type of cancer closely linked to asbestos exposure. Find out the signs and symptoms of malignant mesothelioma and how to protect yourself.
Neuroblastoma most commonly affects children age 5 and younger. It's the most common form of cancer in babies.
Nonalcoholic fatty liver disease is associated with obesity and diabetes. Lifestyle changes may prevent it from becoming serious.
Noroviruses cause an intestinal flu-like illness that typically resolves within days. Norovirus infection is highly contagious, especially in closed settings like hospitals and cruise ships.
Pancreatic cancer is often fatal. Find out which new treatments offer hope.
The pain of pancreatitis, an inflammation of the pancreas, can last for days, or in chronic cases, for years. Pancreatitis can lead to serious complications.
Peptic ulcers are painful sores that commonly affect the lining of your stomach and upper small intestine. The most frequent cause is a treatable infection.
Pituitary tumors are abnormal growths in the pituitary gland in the brain. Most are noncancerous (benign). Some may cause overproduction of hormones and associated problems.
Pulmonary fibrosis results from scar tissue that forms in your lungs. This affects your ability to breathe and obtain enough oxygen.
Comprehensive overview covers symptoms, treatment of this uncommon digestive condition in infants.
Sheehan's syndrome is a rare pituitary gland disorder that occurs in women usually as a result of severe blood loss during childbirth.
Reduce your risk of stomach cancer by eating more fruits and vegetables.
Takayasu's arteritis is an uncommon form of vasculitis that affects the large arteries.
All teens feel down from time to time. But if negative feelings persist or start to interfere with daily life, it might be depression.
The most common throat cancers are linked to smoking and excessive alcohol use.
Most thyroid nodules — lumps in the thyroid gland — cause no problems. But nodules that affect swallowing, produce excess thyroid hormone or are malignant require treatment.
Toxic hepatitis is liver damage that occurs when your liver isn't able to break down certain toxins — including common pain relievers such as Tylenol.
Type 1 diabetes is a lifelong — sometimes frightening — condition, but it doesn't need to slow your child down. Learn more about managing type 1 diabetes.
Lacking certain vitamins can lead to vitamin deficiency anemia. Find out which vitamins are linked to this condition.
Wegener's granulomatosis is an uncommon disease that causes blood vessel inflammation that can damage lungs, kidneys and other organs. Untreated, it can be fatal.
Whipple's disease is a rare bacterial infection that affects primarily the gastrointestinal system, and can be treated successfully with antibiotics.
In Zollinger-Ellison syndrome, tumors in the pancreas or duodenum secrete a hormone called gastrin that leads to excessive stomach acid and ulcers.
Aug. 26, 2014
- Evans AT, et al. Approach to the patient with weight loss. http://www.uptodate.com/home. Accessed April 9, 2014.
- Swartz MH. Textbook of Physical Diagnosis. 7th ed. Philadelphia, Pa.: Saunders Elsevier, 2014. http://www.clinicalkey.com. Accessed April 9, 2014.
- Wong CJ. Involuntary weight loss. Medical Clinics of North America. 2014;98:625.
- McMinn J, et al. Investigation and management of unintentional weight loss in older adults. British Medical Journal. 2011;342:d1732.
- AskMayoExpert. Abnormal weight loss. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2012.
- Wilkinson JW (expert opinion). Mayo Clinic, Rochester, Minn. May 13, 2014.