Stroke

Clinical Trials

Below is a list of Stroke clinical trials from the clinical trials database at Mayo Clinic.

This list includes only trials about which Mayo researchers choose to publish information. Mayo Clinic may be conducting other trials which are not in this database. Mayo's clinical trials include experimental treatments, often unavailable elsewhere, which frequently lead to improved patient care for people worldwide. Patients should ask their doctor at Mayo about clinical trials appropriate for their situation.

Carotid Revascularization Endarterectomy vs. Stenting Trial (CREST)
This study is being done to compare the results of treating blockages in carotid arteries with either carotid endarterectomy (surgery) OR carotid stent procedure. Carotid endarterectomy is an operation on the carotid artery where the thickened area of the artery is removed through an incision in the neck and is performed under general or local anesthesia. Carotid stenting is a procedure where a metal device called a stent is placed in the narrowed part of the carotid artery to hold it open and is performed under local anesthesia.

The study includes a lead-in phase for credentialing of interventionalists, beyond their initial training and certification requirements.
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Comparison of People with History of Ischemic Stroke to Those who Haven't had a Stroke
The purpose of this research study is to test the association between ischemic stroke and variations in genes that are involved in the blood-clotting cascade.

The Ischemic Stroke Genetics Study (ISGS) is a prospective, multicenter, genetic association study. The broad, long-term objective of ISGS is to define the molecular basis for inherited ischemic stroke risk. The study focuses on the hemostatic system because of overwhelming evidence for the etiological relevance of thrombosis in ischemic stroke.

We will test the hypothesis that variations in the beta fibrinogen gene and genes encoding for 3 platelet receptors account for a portion of the inherited risk for ischemic stroke.
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Sibling's with a History of Stroke Sought for Study
The purpose of this research study is to try and identify the genes that increase the risk of developing a stroke.

Genes influencing cholesterol, blood pressure, clotting and other as yet poorly recognized factors may increase the risk of having a stroke. Stroke is a common and often devastating condition. A stroke occurs when the blood supply to the brain is interrupted and brain tissue is deprived of oxygen and nutrients.

Every year about 750,000 Americans experience a stroke; about 160,000 of these people die. Stroke is the leading cause of adult disability and only cardiovascular diseases and cancer cause more deaths annually in the United States.
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Walking Study for Inpatient Stroke Rehabilitation: A Multi-Center Randomized Clinical Trial of Verbal Encouragement and Measuring Time During a 10-Meter Walk to Improve Walking Speed and Distance
The purpose of this study is to determine whether encouragement to walk faster and feedback on walking speed during inpatient rehabilitation can improve recovery of walking speed in people who have experienced a stroke. The results of this study may help doctors and therapists understand the ways in which walking speed can be improved after stroke.
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