Primary Sclerosing Cholangitis

Clinical Trials

Below is a list of Primary Sclerosing Cholangitis clinical trials from the clinical trials database at Mayo Clinic.

This list includes only trials about which Mayo researchers choose to publish information. Mayo Clinic may be conducting other trials which are not in this database. Mayo's clinical trials include experimental treatments, often unavailable elsewhere, which frequently lead to improved patient care for people worldwide. Patients should ask their doctor at Mayo about clinical trials appropriate for their situation.

P.R.O.G.R.E.S.S.: PSC Resource Of Genetic Risk, Environment and Synergy Studies
This research study is being done to unravel the genetic predisposition to primary sclerosing cholangitis (PSC). Evidence indicates that the inherited genetic material passed from parents to their children as well as environmental factors contribute to the development of PSC. This study will help us develop novel ways to prevent, diagnose and treat PSC.

Because we look at how PSC may be passed down in families, we are also interested in studying family members of PSC patients who are not affected by PSC.
Read more

Understanding the Genetic Predisposition to the Development of Primary Biliary Cirrhosis (PBC)
This research study is being done to better understand what causes Primary Biliary Cirrhosis (PBC). Current evidence suggests that both genes (the inherited genetic material passed from parents to their children) and environmental factors play a role in the development of PBC. This study will help us better understand the cause(s) of PBC and hopefully find new ways to its prevention, diagnosis and treatment.
Because we are also looking at how PBC may be passed down in families, we are identifying families in which more than one family member has a history of PBC. We are also interested in studying family members of PBC patients who have anti-mitochondrial-antibodies in their blood. These antibodies are present in almost all persons with PBC and are also found in some of their family members who, however, have no evidence of PBC.
Read more