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Peptic ulcers are open sores that develop in the lining of your stomach, esophagus or the upper part of the small intestine (duodenum). An ulcer often causes burning pain that can worsen when your stomach is empty. Peptic ulcers can lead to internal bleeding (bleeding ulcer), infection or other digestive problems. Medication can manage your pain and encourage healing.
Mayo Clinic in Rochester, Minn., ranks No. 1 for digestive disorders in the U.S. News & World Report Best Hospitals rankings. Mayo Clinic in Scottsdale, Ariz., and Mayo Clinic in Jacksonville, Fla., are ranked high performing for digestive disorders by U.S. News & World Report.
Read more about peptic ulcers.
Most ulcers are related to infection by the H. pylori bacterium, although most people with H. pylori infection do not get peptic ulcers. See Questions and Answers about H. pylori.
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