Osteosarcoma

Clinical Trials

Below is a list of Osteosarcoma clinical trials from the clinical trials database at Mayo Clinic.

This list includes only trials about which Mayo researchers choose to publish information. Mayo Clinic may be conducting other trials which are not in this database. Mayo's clinical trials include experimental treatments, often unavailable elsewhere, which frequently lead to improved patient care for people worldwide. Patients should ask their doctor at Mayo about clinical trials appropriate for their situation.

Optimizing Treatment Strategies for Surgically Treatable Osteosarcoma, Based on Response to Pre-operative Chemotherapy.
Study doctors would like to find out how best to treat subjects with osteosarcoma by comparing how subjects do when treated with different anti-cancer drugs. The standard anti-cancer drugs used to treat subjects with osteosarcoma are methotrexate, doxorubicin (also called adriamycin) and cisplatin. These three drugs together are called MAP. This study is being done to:
- See if adding ifosfamide and etoposide (VP-16) to chemotherapy will help get rid of the disease in subjects who have a poor tumor response to MAP alone.
- See if adding a "biologic" drug called interferon after MAP chemotherapy can help get rid of the disease in subjects who have a good tumor response to standard chemotherapy. This study will use pegylated interferon alfa-2b, interferon that has been changed to last longer in the body so it can be given less often.
Read more

The Use of Chemotherapy Medications, Gemcitabine (Gemzar) and Docetaxel (Taxotere) in the Treatment of Ewing Sarcoma, Osteosarcoma, or Chondrosarcoma
This study is being done to:
-See if the chemotherapy drugs gemcitabine (Gemzar) and docetaxel (Taxotere), when given together, may help to fight cancer of the bone or soft tissue. Each of these drugs is approved by the US Food and Drug Administration (FDA) for the treatment of some kinds of cancer, such as cancer of the pancreas and lung, but they are not approved for this type of cancer, so in this study they are called investigational drugs.
-See what effects (good and bad) gemcitabine and docetaxel have on the patient and the tumor.
-See how a patient's body processes the gemcitabine and docetaxel.
-(When possible), to do genetic research studies on a sample of a patient's tumor tissue.
Read more