Tuesday, December 30, 2003
It's true that some people who participate in research studies and take inactive medications called placebos do see health improvements. People taking placebos have experienced reduced pain, healed ulcers, eased nausea and even warts disappeared.
The January issue of Mayo Clinic Women's HealthSource details several theories on how the placebo effect might work:
Benefit from attention: In a placebo-controlled research study, patients often have frequent and intensive medical attention. Some people respond favorably.
Stimulus response: People may have a trained positive response to taking a pill or receiving treatment, whether it's real or not.
Beliefs or expectations, including the meaning you attach to a treatment: A person with positive expectations of the treatment may experience the placebo effect more than someone with lower expectations.
Relationship with your doctor: A person whose doctor is supportive and positive may experience more benefit from a placebo — or the standard treatment — than someone who doesn't have that relationship.
Pleasing your doctor: You feel better because — consciously or unconsciously — you want to show your doctor that you're a good patient and you appreciate the care.
Probably a combination of many psychological and physiological mechanisms are at work. Research studies and theories hold important clues to solve the mystery behind the placebo effect, but more research is needed to examine how these factors interplay to produce this healing force.
Mayo Clinic in Rochester
Carol Lammers
507-284-5005 (days)
507-284-2511(evenings)
email: newsbureau@mayo.edu
Mayo Clinic in Jacksonville
Erik Kaldor
904-953-2302
Mayo Clinic in Scottsdale
Anne Tewksbury
480-301-4368
Mayo Clinic Women's HealthSource is published monthly to help women enjoy healthier, more productive lives. Revenue from subscriptions is used to support medical research at Mayo Clinic. To subscribe, please call 800-876-8633, extension 9PK1.
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