Myocarditis

Clinical Trials

Below is a list of Myocarditis clinical trials from the clinical trials database at Mayo Clinic.

This list includes only trials about which Mayo researchers choose to publish information. Mayo Clinic may be conducting other trials which are not in this database. Mayo's clinical trials include experimental treatments, often unavailable elsewhere, which frequently lead to improved patient care for people worldwide. Patients should ask their doctor at Mayo about clinical trials appropriate for their situation.

Genetic Basis of Left Ventricular Recovery in Congestive Heart Failure
Research suggests that many cases of cardiomyopathy are caused initially by a virus, which then causes the body's immune system to attack the heart. This is an inflammatory
reaction which leads to heart damage. In some patients with this disorder, the heart will recover significantly over the first year, while others will be left with a chronically weak heart. The purpose of this research study is to determine if persons who present with the recent onset of primary cardiomyopathy have a better chance of recovery if they have certain genes and for a stronger inflammatory reaction.
Read more

Immunosuppressive Treatment in Patients with Giant Cell Myocarditis
The purpose of this research study is to determine if immunosuppressive treatment with an investigational drug called muromonab-CD3 can improve survival or decrease the need for heart transplantation in individuals with giant cell myocarditis. This study compares two different combinations of these drugs to evaluate the effectiveness and safety of this treatment. In this study,
muromonab-CD3, cyclosporine, and steroids will be compared with cyclosporine and steroids without muromonab-CD3.
Read more

The Giant Cell Myocarditis Treatment Trial - Screening Only
This study is being done to identify the causes of giant cell myocarditis (severe inflammation of the heart).

Giant cell myocarditis is a serious disease of the heart that often causes death or need for a heart transplant. It is a rare disease, which has made it difficult to be certain regarding the best treatment.
Read more