Myelofibrosis with Myeloid Metaplasia

Research

Mayo Clinic physicians have a long track record for evaluating experimental therapies in an attempt to find a medical cure for myelofibrosis. Mayo's research program includes basic scientists and clinicians who test the latest drug therapies for usefulness in treating myelofibrosis. Drugs that appear promising and safe in the laboratory can be offered to patients in clinical trials through the Mayo Clinic Cancer Center . The list of clinical trials changes constantly. Hematologists consult with each patient to determine the appropriate clinical trial or other therapy. At Mayo, physicians and researchers are committed to finding better treatment options for myelofibrosis patients.

Select Publications

Maziarz RT, Mesa RA, Ayalew T: Allogeneic Stem Cell Transplantation for Chronic Myeloproliferative Disorders and Myelodysplastic Syndromes: The Question Is When? Mayo Clinic Proc. Aug 2003;78(8):941-43. View PDF of article.

Mesa RA. Myelofibrosis with myeloid metaplasia: therapeutic options in 2003. Curr Hematol Rep. 2003 May;2(3):264-70. Review. [Abstract]

Mesa RA, Steensma DP, Pardanani A, Li CY, Elliott M, Kaufmann SH, Wiseman G, Gray LA, Schroeder G, Reeder T, Zeldis JB, Tefferi A. A phase 2 trial of combination low-dose thalidomide and prednisone for the treatment of myelofibrosis with myeloid metaplasia. Blood. 2003 Apr 1;101(7):2534-41. Epub 2002 Nov 27. [Abstract]

Elliott MA, Mesa RA, Li CY, Hook CC, Ansell SM, Levitt RM, Geyer SM, Tefferi A. Thalidomide treatment in myelofibrosis with myeloid metaplasia. Br J Haematol. 2002 May;117(2):288-96. [Abstract]

Tefferi A. Myelofibrosis with myeloid metaplasia. N Engl J Med. 2000 Apr 27;342(17):1255-65. Review. [No abstract available]