Multiple System Atrophy

Diagnosis

Patients with multiple system atrophy eventually develop symptoms of Parkinson's disease (slowed movement, rigidity) and autonomic dysfunction (problems with blood pressure, heart rate, digestion, sexual function, etc.), but patients often develop one set of symptoms before the other, making diagnosis difficult.

No test can diagnose multiple system atrophy. A neurologist makes the diagnosis based on the history of symptoms, a physical examination and by ruling out other causes.

Tests that may help confirm the diagnosis include checking plasma norepinephrine levels and breakdown, and an MRI (magnetic resonance imaging) of the head to rule out other causes.

Mayo Clinic has the experience and tools to help make an accurate diagnosis.