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Multiple Myeloma

Research

Mayo Clinic's Hematologic Malignancies Program has a strong tradition of advanced research to improve the diagnosis and treatment of blood cancers. Mayo's myeloma program is the oldest and largest in the U.S. Its researchers study every aspect of the disease and have been recognized by their peers and by funding agencies for many discoveries.

Funded by the Hematologic Malignancies Fund of Mayo Clinic and the National Institutes of Health, the myeloma laboratory holds a prestigious project grant for multiple myeloma research. Current research efforts include:

  • Multiple myeloma's causes and genetics
  • The mechanism whereby monoclonal gammopathy (MGUS) transforms into multiple myeloma
  • Blood-vessel formation and its regulatory action on multiple myeloma
  • The role of specific surface markers and circulating cells in the biology of multiple myeloma
  • New treatments such as immune targeting and gene therapy

In the Mayo Clinic tradition of collaborative work, myeloma researchers meet with physicians and basic scientists in other specialties to share knowledge. The laboratory's cell and serum bank contains samples from thousands of multiple myeloma patients. These samples are used for myeloma research and are shared with investigators all over the world interested in moving toward a cure for this disease.

Publications

See publications by Mayo staff on multiple myeloma on PubMed, a service of the National Library of Medicine.

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