Diagnosing mesothelioma is often difficult because the symptoms are similar to those of several other conditions. Mayo Clinic has an experienced staff and the latest technologies for making an accurate diagnosis.
Reviewing a patient's medical history, including a history of asbestos exposure, is the first step in diagnosing mesothelioma.
A complete physical examination may include X-rays of the chest or abdomen and lung function tests. A computed tomography (CT) scan or an MRI may also be useful.
A CT scan produces detailed pictures of areas inside the body using a computer linked to an X-ray machine.
An MRI uses powerful magnets and radio waves to produce a detailed, three-dimensional view of the areas where mesothelioma is suspected.
The most definitive test for diagnosing mesothelioma is a biopsy (tissue sample) of affected or suspicious tissues, with microscopic examination by a pathologist. The pathologist usually also looks for the rate of growth and biological virulence (strength) of the tumor.
Once a diagnosis is made, physicians determine the stage (progression) of the cancer by using a chest X-ray, CT scan or an MRI to determine its location within the body and to select the most effective treatment.