In most cases, clinical manifestations of MEN 1 do not occur until a person's 20s or 30s. However, at-risk children may be tested for the genetic mutation associated with MEN 1.
If genetic test results confirm the presence of the genetic mutation, specialists at Mayo Clinic may recommend that the child be screened regularly, starting between ages 10 and 15, for hyperthyroidism and other clinical expressions of the disease. Blood tests help to track any changes in biochemical markers associated with the MEN 1 progression.
Treatments for children or adolescents who experience tumors and other expressions of MEN 1 are similar to adult treatments for multiple endocrine neoplasia. Children are most likely to have pituitary tumors or abnormalities in parathyroid hormone (PTH) levels.
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