Axial T2 FLAIR and post-gadolinium T1 images of children with MS
A, Axial T2 FLAIR image of a 5-year-old boy with multiple sclerosis. Newly developed lesions aren't well demarcated and show contrast enhancement after gadolinium administration. B, Axial T2 FLAIR image of a 6-year-old girl with acute disseminated encephalomyelitis in the setting of viral prodromal illness, with no gadolinium contrast. The lesions aren't well demarcated and show involvement of both cerebral white and gray matter. C, Post-gadolinium T1 image of a 17-year-old male with clinical symptoms of mild ataxia and mild unilateral weakness. Numerous well-demarcated lesions are visible. Subsequent clinical events corresponding with new MRI lesions developed over time.