Comparison of viral load in spinal cords of 3Dpol transgenic mice and normal mice

Expression of the 3D polymerase gene (3D^pol) in mice reduces viral load after infection. Viral load in the spinal cords of 3D^pol transgenic mice and normal mice three days after being infected with one of three different viruses: encephalomyocarditis virus (EMCV), pseudorabies virus (PRV), or vesicular stomatitis virus (VSV). The transgenic mice have substantially less of the three viruses than normal mice.