Schematic of norepinephrine reuptake into presynaptic nerve terminals

Schematic of norepinephrine reuptake into presynaptic nerve terminals by the uptake-1 mechanism (βAR, β-adrenergic receptor; α1AR, α1 adrenergic receptor; COMT, catechol-O-methyltransferase; MAO, monoamine oxidase; NE, norepinephrine).