Biobank research model

The research model used by the Division of Cardiovascular Surgery at Mayo Clinic. A large-scale biobanking effort is being implemented that will allow researchers to conduct molecular screens on human tissue to identify novel molecules contributing to cardiovascular disease. Genetically modified mice and in vitro models are used to identify mechanisms through which these molecules drive disease processes. Studies in humans and animal models can then be conducted to identify pharmacologic interventions that will slow or reverse the progression of disease.